Self-Collection of Vaginal Swabs Among Adolescent Girls in a School-Setting in East Africa
Self-Collection of Vaginal Swabs Among Adolescent Girls in a School-Setting in East Africa
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DOI：
10.1097/olq.0000000000000990
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发表时间：
2019-05-01
影响因子：
3.1
通讯作者：
Mbidde, Edward Katongole
中科院分区：
文献类型：
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作者：
Francis, Suzanna C.;Miiro, George;Mbidde, Edward Katongole
很少有研究评估撒哈拉以南非洲年轻女性（包括学校）自我采集阴道拭子的可接受性。我们评估了2个条件的可接受性，在中学的拭子自我收集在恩德培，Uganda.Methods同意从3所中学的家长同意的女孩提供了指示采样，并随机分配到自我收集的阴道拭子有或没有护士的协助，以帮助正确放置拭子。通过革兰氏染色检测拭子的细菌性阴道病。参与者随访后1至2天，1至2周，并邀请一个定性interview.Results总体96名女孩入组（中位年龄，16岁;四分位数间距，15-17岁）。在第一次随访时，两组参与者都报告说，样本采集的说明很容易理解，他们对自我采集感到满意。护士协助组的女孩比没有护士协助组的女孩感觉更不放松（27%比50%，P = 0.02），但更有信心正确收集样本（96%比83%，P = 0.04）。大约一半（47%）的参与者同意自我采样是痛苦的，但几乎所有（94%）的人都会再次参加类似的研究。定性数据显示，参与者更喜欢自己收集没有护士的协助，以保护隐私。细菌性阴道病的患病率为14%（95%置信区间，8- 22h.Conclusions），在这种情况下，自我收集的阴道拭子在中学是可以接受的和可行的，和女孩更喜欢自己收集没有护士的协助。自我采集拭子是检测、治疗和控制女孩和年轻妇女生殖道感染的重要工具。
Background Few studies have evaluated the acceptability of self-collected vaginal swabs among young women in sub-Saharan Africa, including in school settings. We evaluated the acceptability of 2 conditions for the self-collection of swabs in secondary schools in Entebbe, Uganda.Methods Assenting girls with parental consent from 3 secondary schools were provided instructions for sampling, and randomly allocated to self-collection of vaginal swabs with or without nurse assistance to help with correct placement of the swab. Swabs were tested for bacterial vaginosis by Gram stain. Participants were followed up after 1 to 2 days and 1 to 2 weeks and invited for a qualitative interview.Results Overall 96 girls were enrolled (median age, 16 years; interquartile range, 15-17 years). At the first follow-up visit, participants in both arms reported that instructions for sample collection were easy to understand, and they felt comfortable with self-collection. Girls in the nurse assistance arm reported feeling less relaxed (27% vs. 50%, P = 0.02) than those in the arm without nurse assistance, but more confident that they collected the sample correctly (96% vs. 83%, P = 0.04). About half (47%) of participants agreed that self-sampling was painful, but almost all (94%) would participate in a similar study again. Qualitative data showed that participants preferred self-collection without nurse assistance to preserve privacy. Bacterial vaginosis prevalence was 14% (95% confidence interval, 8-22).Conclusions In this setting, self-collection of vaginal swabs in secondary schools was acceptable and feasible, and girls preferred self-collection without nurse assistance. Self-collection of swabs is an important tool for the detection, treatment and control of reproductive tract infections in girls and young women.