Haemaphysalis longicornis Ticks as Reservoir and Vector of Severe Fever with Thrombocytopenia Syndrome Virus in China.
Haemaphysalis longicornis Ticks as Reservoir and Vector of Severe Fever with Thrombocytopenia Syndrome Virus in China.
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长角血蜱是中国发热伴血小板减少综合征病毒的宿主和载体
DOI：
10.3201/eid2110.150126
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发表时间：
2015-10
影响因子：
11.8
通讯作者：
Yu XJ
中科院分区：
文献类型：
--
作者：
Luo LM;Zhao L;Wen HL;Zhang ZT;Liu JW;Fang LZ;Xue ZF;Ma DQ;Zhang XS;Ding SJ;Lei XY;Yu XJ
病毒可在蜱虫中传播，也可通过蜱虫叮咬传播给小鼠。发热伴血小板减少综合征（SFTS）是由一种新发现的静脉病毒SFTS病毒（SFTSV）引起的东亚新发出血热。长角血蜱被怀疑是SFTSV的媒介。为了确定SFTSV是否可以在蜱之间、蜱向动物传播、动物向蜱传播，我们进行了长角蜱发育阶段和蜱与小鼠之间的传播研究。利用反转录PCR方法分析了山东省植被采集的长角蜱感染SFTSV的流行情况。结果表明，采集到的蜱中SFTSV的流行率很低（0.2%，8/ 3300只），并且我们发现，以感染SFTSV的小鼠为食的蜱可以获得病毒并经尿道和经卵巢传播给其他发育阶段的蜱。此外，感染sftsv的蜱虫可以通过进食将病毒传播给小鼠。提示蜱可能是SFTSV的媒介和宿主。
Transstadial and transovarial virus transmission occur among ticks, and transmission to mice can occur through a tick bite. Severe fever with thrombocytopenia syndrome (SFTS) is an emerging hemorrhagic fever in East Asia caused by SFTS virus (SFTSV), a newly discovered phlebovirus. The Haemaphysalis longicornis tick has been suspected to be the vector of SFTSV. To determine whether SFTSV can be transmitted among ticks, from ticks to animals, and from animals to ticks, we conducted transmission studies between developmental stages of H. longicornis ticks and between ticks and mice. Using reverse transcription PCR, we also analyzed the prevalence of SFTSV infection among H. longicornis ticks collected from vegetation in Shandong Province, China. Our results showed a low prevalence of SFTSV among collected ticks (0.2%, 8/3,300 ticks), and we showed that ticks fed on SFTSV-infected mice could acquire the virus and transstadially and transovarially transmit it to other developmental stages of ticks. Furthermore, SFTSV-infected ticks could transmit the virus to mice during feeding. Our findings indicate ticks could serve as a vector and reservoir of SFTSV.