Dominant microbial volatile organic compounds in 23 US homes.
Dominant microbial volatile organic compounds in 23 US homes.
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美国 23 个家庭的主要微生物挥发性有机化合物。
DOI：
10.1016/j.chemosphere.2012.06.066
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发表时间：
2013
期刊：
影响因子：
8.8
通讯作者：
Catherine C. Beaucham
中科院分区：
文献类型：
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作者：
T. Ryan;Catherine C. Beaucham
将微生物挥发性有机化合物（MVOC）与产生它们的物种联系起来，可能会开辟一条更快速可靠的化学方法来检测霉菌问题的道路，特别是对于隐藏在墙腔或小封闭空间中的霉菌。这项研究相关联的占主导地位的MVOCs在一个方便的样本，23个家庭与霉菌的物种。通过比较地下室与主楼层区域，在家中评估霉菌生长的三个半定量预测因子（“MOW分数”）。收集MVOC样品并通过GC/MS进行分析。Aerotek N-6采样器与MVOC采样器位于同一位置以收集生物气溶胶。浓度和流行率数据的19个明确的MVOC进行了比较与生物气溶胶数据。与主楼层相比，地下室位置的霉菌预测因子得分升高。在鉴定的23个霉菌属中，优势属（排名发生）为枝孢属、青霉属、担子菌属和放线菌属。MVOC 2-辛烯-1-醇、3-辛烯酮、2-庚酮、1-辛烯-3-醇和1-丁醇的平均浓度最高（11-37μgm−3），但在这些无问题的家庭中，与主楼层生活区相比，地下室位置的MVOC没有显著升高。使用不太保守的单尾显著性检验，地下室中2-辛烯-1-醇的平均浓度较高（p<0.040），3-辛烯酮和1-辛烯-3-醇均升高（p<0.095）。家庭之间MVOC发生的差异最大，在地下室位置发现的MVOC通常在生活区以类似的浓度和频率检测到。基于这些发现，C8 MVOC有望作为与最常见的霉菌属相关的真菌生长的总体指标。
Associating Microbial Volatile Organic Compounds (MVOCs) with the species producing them may open the path to more rapid and reliable chemical methods to detect mold problems, especially for mold hidden in wall cavities or small enclosed spaces. This study associated the dominant MVOCs in a convenience sample of 23 homes with the mold species present. Three semi-quantitative predictors of mold growth (“MOW scores”) were assessed in the homes through a comparison of basement to main floor areas. MVOC samples were collected and analyzed by GC/MS. Aerotek N-6 samplers were co-located with the MVOC samplers to collect bioaerosols. Concentration and prevalence data for 19 definitive MVOCs were compared with the bioaerosol data. Mold predictor scores were elevated in basement locations as compared with main floor areas. Of the 23 mold genera identified, the predominant genera (ranked occurrences) were Cladosporium, Penicillium, Basidiomycetes, and Aspergilli. The MVOCs 2-octen-1-ol, 3-octenone, 2-heptanone, 1-octen-3-ol, and 1-butanol showed the highest average concentrations (11–37μgm−3), but no single MVOC was significantly elevated in basement locations as compared with main floor living areas in these non-problematic homes. Using a less conservative one-tail test of significance, average 2-octen-1-ol concentrations in basements were higher (p<0.040), and both 3-octenone and 1-octen-3-ol were elevated (p<0.095). Differences in MVOC occurrence were greatest between homes, with MVOCs found in basement locations typically detected in living areas at similar concentrations and frequencies. Based on these findings, the C8MVOCs show promise as gross indicators of fungal growth related to the most frequently found mold genera.