Adenovirus nephritis and obstructive uropathy in a renal transplant recipient: case report and literature review.
Adenovirus nephritis and obstructive uropathy in a renal transplant recipient: case report and literature review.
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DOI：
10.1093/ndtplus/sfq024
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发表时间：
2010-08
期刊：
影响因子：
--
通讯作者：
Glicklich D
中科院分区：
文献类型：
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作者：
Kolankiewicz LM;Pullman J;Raffeld M;Kopp JB;Glicklich D
我们报告一个不寻常的情况下，腺病毒性肾炎的45岁女子谁提出发烧，肉眼血尿，急性肾损伤和梗阻性尿路病17个月后肾移植。免疫组化证实为腺病毒性肾炎。我们确定了其他10例腺病毒肾炎的免疫组化证实。阻塞性尿路病以前仅报告过一次肾移植受者腺病毒性肾炎。与其他报告相反，该病例系列显示急性腺病毒病后肾功能可能不总是恢复到基线水平。肾移植患者在移植后早期和晚期出现发热、血尿、急性肾损伤和肾积水时，应考虑腺病毒性肾炎。
We report an unusual case of adenoviral nephritis in a 45-year-old woman who presented with fever, gross haematuria, acute kidney injury and obstructive uropathy 17 months following renal transplantation. Adenoviral nephritis was confirmed with immunohistochemistry. We identified 10 other published cases of adenoviral nephritis proven by immunohistochemistry. Obstructive uropathy has been reported only once before in a renal transplant recipient with adenoviral nephritis. Contrary to other reports, this case series shows that renal function may not always recover to baseline following the acute adenoviral disease. Adenoviral nephritis should be considered in the renal transplant patient with fever, haematuria, acute kidney injury and hydronephrosis in both the early and late post-transplant periods.