0.25-PERCENT AND 0.4-PERCENT AMINE FLUORIDE GEL FOR WEEKLY TOPICAL APPLICATION - AN INVIVO STUDY ON HUMAN DENTAL ENAMEL
0.25-PERCENT AND 0.4-PERCENT AMINE FLUORIDE GEL FOR WEEKLY TOPICAL APPLICATION - AN INVIVO STUDY ON HUMAN DENTAL ENAMEL
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每周局部使用的 0.25% 和 0.4% 氟化胺凝胶 - 对人类牙釉质的体内研究
DOI：
10.1159/000260975
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发表时间：
1986
期刊：
影响因子：
4.2
通讯作者：
D. Purdell
中科院分区：
文献类型：
--
作者：
J. Goorhuis;D. Purdell
在双盲交叉研究中，研究了安慰剂牙膏、安慰剂凝胶、氟化胺牙膏、安慰剂凝胶、氟化胺牙膏、0.25%氟化胺牙膏和氟化胺牙膏、0.4%氟化胺凝胶的体内再矿化效果。将人工脱矿牙釉质平坦板放置于部分义齿的颊缘内。在3周的实验期间，发现2个氟化凝胶组的再矿化增加明显更多。这发生在表层和亚表层病变中，并导致病变深度显著减少和硬度增加。建议对于有早期釉质损伤的患者，如果这些凝胶是在正常的预防措施下形成的或未能重新矿化，则应考虑每周使用这些凝胶。
In a double-blind crossover study the remineralizing effects of the combinations: placebo toothpaste, placebo gel; amine fluoride toothpaste, placebo gel; amine fluoride toothpaste, 0.25% F–– amine fluoride gel and amine fluoride toothpaste, 0.4% F–– amine fluoride gel were investigated in vivo. Artificially demineralized flattened enamel slabs were placed in the buccal flanges of partial dentures. It was found during the 3-week experimental periods that there was a significantly higher increase in remineralization in the 2 fluoride gel groups. This occurred in both the surface layer and subsurface lesion and resulted in a significant decrease in lesion depth and increase in hardness. It is suggested that the weekly use of these gels should be considered in patients with early enamel lesions if they are formed during, or fail to remineralize under, a normal preventive regime.