Can low b value diffusion weighted imaging evaluate the character of cerebrospinal fluid dynamics?
Can low b value diffusion weighted imaging evaluate the character of cerebrospinal fluid dynamics?
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DOI：
10.1007/s11604-018-0790-8
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发表时间：
2019-02-01
影响因子：
2.1
通讯作者：
Murata, Katsutoshi
中科院分区：
文献类型：
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作者：
Taoka, Toshiaki;Naganawa, Shinji;Murata, Katsutoshi
目的探讨低b值弥散加权成像（DWI）是否可以显示脑脊液（CSF）动力学的变化。材料与方法本回顾性研究的受试者包括脑室扩张患者（n=50）和对照组（n=50）。采用评分法评价b=500s/mm(2)DWI上侧脑室、第3脑室、第4脑室、脑沟、外侧裂的脑脊液信号强度。还评估了透明隔附近的信号空洞结果。结果脑室扩张受试者的侧脑室和第三脑室的脑脊液信号强度明显较低。在对照组中，侧裂中信号缺失的评分与年龄呈显着正相关。然而，其他领域并未表现出与年龄的显着相关性。透明隔附近特征信号空洞的出现与心室扩张显着相关。结论我们目前的研究表明，b=500s/mm(2) DWI 上的 CSF 信号强度可能显示 CSF 动力学的变化，可能有助于评估 CSF 动力学的忽视。
PurposeWe aimed to investigate whether low b value diffusion-weighted imaging (DWI) can show the change of cerebrospinal fluid (CSF) dynamics.Materials and methodsThe subjects of this retrospective study consisted of patients with ventricular dilatation (n=50) and controls (n=50). The CSF signal intensity on the b=500s/mm(2) DWI was evaluated by a scoring method in the lateral, 3rd and 4th ventricles, the cerebral sulci and the Sylvian fissure. The signal void findings adjacent to the septum pellucidum were also evaluated.ResultsThe CSF signal intensities were significantly less in lateral ventricle and 3rd ventricle of the ventricular dilatation subjects. In controls, the score for the signal void in the Sylvian fissure showed a significant positive correlation with age. However, other areas did not show a significant correlation with age. The appearance of the characteristic signal void adjacent to the septum pellucidum showed a significant correlation with ventricular dilatation.ConclusionOur current study suggests that the CSF signal intensity on the b=500s/mm(2) DWI may show the changes in CSF dynamics and might be useful to evaluate the overlook of CSF dynamics.