TWENTY-EIGHT CASES OF HUMAN HEART-LUNG TRANSPLANTATION
TWENTY-EIGHT CASES OF HUMAN HEART-LUNG TRANSPLANTATION
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人心肺移植28例
DOI：
10.1016/s0140-6736(86)90881-0
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
S. Jamieson
中科院分区：
文献类型：
--
作者：
C. Burke;J. Baldwin;A. Morris;N. Shumway;J. Theodore;H. Tazelaar;C. McGregor;E. Robin;S. Jamieson
从1981年3月到1985年8月，在同一个机构的27名病人中进行了28例心肺移植手术。8例患者在围手术期死亡，与既往胸外科手术相关的粘连被证明是术后出血的主要风险因素。20例长期存活者中有一半发生闭塞性细支气管炎，平均术后11.2个月（范围2-35个月）：其中4例死亡，3例功能受限，2例成功接受皮质类固醇治疗，其余1例成功再次移植。另外10例长期存活者在移植后平均22.6个月（范围4-42个月）恢复正常生活，肺功能基本正常。所有存活的患者都有与环孢素肾毒性相关的肾损害证据。结果表明，虽然心肺移植与基本正常的长期肺功能是兼容的，但该程序还不应被视为常规的临床干预。
Between March, 1981, and August, 1985, twenty-eight heart-lung transplant operations were done in 27 patients at a single institution. 8 patients died in the perioperative period and adhesions related to previous thoracic surgery proved to be a major risk factor for postoperative haemorrhage. Obliterative bronchiolitis developed in half of the 20 long-term survivors, a mean of 11·2 months (range 2-35 months) after surgery: 4 of these patients died, 3 are functionally limited, 2 were successfully treated with corticosteroids, and the remaining patient was successfully retransplanted. The other 10 long-term survivors returned to a normal life with essentially normal pulmonary function measured at a mean of 22·6 months (range 4-42 months) after transplantation. All the surviving patients have evidence of renal impairment related to cyclosporin nephrotoxicity. The results indicate that, although heart-lung transplantation is compatible with essentially normal long-term pulmonary function, the procedure should not yet be regarded as a routine clinical intervention.
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影响因子：
158.5
作者：
MYERS, BD;ROSS, J;PERLROTH, M
通讯作者：
PERLROTH, M
人类心肺移植的生理学方面。
影响因子：
9.6
作者：
Theodore,J;Jamieson,SW;Burke,CM;Reitz,BA;Stinson,EB;VanKessel,A;Dawkins,KD;Herran,JJ;Oyer,PE;Hunt,SA
通讯作者：
Hunt,SA
DOI：
--
发表时间：
1984
期刊：
The Journal of thoracic and cardiovascular surgery
影响因子：
--
作者：
Jamieson,SW;Stinson,EB;Oyer,PE;Baldwin,JC;Shumway,NE
通讯作者：
Shumway,NE
心肺联合移植术后孤立性肺排斥反应。
DOI：
--
发表时间：
1985
期刊：
The Journal of thoracic and cardiovascular surgery
影响因子：
--
作者：
McGregor,CG;Baldwin,JC;Jamieson,SW;Billingham,ME;Yousem,SA;Burke,CM;Oyer,PE;Stinson,EB;Shumway,NE
通讯作者：
Shumway,NE