Serum vasopressin concentrations in critically ill patients
Serum vasopressin concentrations in critically ill patients
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DOI：
10.1097/01.ccm.0000198528.56397.4f
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发表时间：
2006-02-01
影响因子：
8.8
通讯作者：
Dünser, MW
中科院分区：
文献类型：
--
作者：
Jochberger, S;Mayr, VD;Dünser, MW
目的：测定危重病患者血清精氨酸加压素(AVP)浓度。前瞻性研究。设置在一所三级大学教学医院的12张病床的普通和外科重症监护病房。患者：239名混合危重病人和70名健康志愿者。干预。测量和主要结果：记录人口学数据、血流动力学变量、血管加压药用量、血气、入院后24小时内AVP血清浓度、多器官功能障碍评分和预后。入院24小时后，研究组AVP浓度(11.9+/-20.6 pg/m L)显著高于健康对照组(0.92+/-0.38 pg/m L；p
Objective: To measure arginine vasopressin (AVP) serum concentrations in critically ill patients.Design. Prospective study.Setting., Twelve-bed general and surgical intensive care unit in a tertiary, university teaching hospital.Patients: Two-hundred-thirty-nine mixed critically ill patients and 70 healthy volunteers.Interventions. None.Measurements and Main Results: Demographic data, hemodynamic variables, vasopressor drug requirements, blood gases, AVP serum concentrations within 24 hrs after admission, multiple organ dysfunction score, and outcome were recorded. Twenty-four hours after admission, study patients had significantly higher AVP concentrations (11.9 +/- 20.6 pg/mL) than healthy controls (0.92 +/- 0.38 pg/mL; p