The inflation response of the posterior bovine sclera
The inflation response of the posterior bovine sclera
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DOI：
10.1016/j.actbio.2010.06.007
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发表时间：
2010-11-01
影响因子：
9.7
通讯作者：
Nguyen, Thao D.
中科院分区：
文献类型：
--
作者：
Myers, Kristin M.;Coudrillier, Baptiste;Nguyen, Thao D.
开发了一种体外膨胀测试方法来表征牛后巩膜的机械行为。该方法使用数字图像相关性来提供后巩膜表面响应受控加压的空间分辨全场变形图。在 2-6 kPa (15-45 mmHg) 范围内进行了一系列实验，以表征不同压力速率下的加载-卸载位移响应以及不同施加压力下随时间变化的位移响应。位移幅度在视乳头周围区域最大，主要在心尖和视神经乳头之间。此外，结果表明，牛巩膜组织表现出非线性和粘弹性行为，其特征在于速率依赖性位移响应、卸载和蠕变期间的滞后。蠕变速率对施加的压力不敏感，这表明该组织可以在 2-6 kPa 的生理压力范围内建模为准线性粘弹性材料。 (C) 2010 Acta Materialia Inc. 由 Elsevier Ltd 出版。保留所有权利。
An in vitro inflation test method was developed to characterize the mechanical behavior of the bovine posterior sclera. The method used digital image correlation to provide a spatially resolved, full-field deformation map of the surface of the posterior sclera in response to controlled pressurization. A series of experiments were performed in the range of 2-6 kPa (15-45 mmHg) to characterize the load-unload displacement response at various pressure rates and the time-dependent displacement response at different applied pressures. The magnitude of the displacement was largest in the peripapillary region, mainly between the apex and the optic nerve head. Further, the results showed that bovine scleral tissue exhibited nonlinear and viscoelastic behavior characterized by a rate-dependent displacement response, hysteresis during unloading and creep. The creep rate was insensitive to the applied pressure, suggesting that the tissue can be modeled as a quasilinear viscoelastic material in the physiological pressure range of 2-6 kPa. (C) 2010 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.