Computational Tools for Stem Cell Biology.
Computational Tools for Stem Cell Biology.
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DOI:
10.1016/j.tibtech.2016.05.010
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发表时间:
2016-12
影响因子:
17.3
通讯作者:
Cahan, Patrick
中科院分区:
文献类型:
--
作者:
Bian, Qin;Cahan, Patrick
For over half a century, the field of developmental biology has leveraged computation to explore mechanisms of developmental processes. More recently, computational approaches have been critical in the translation of high throughput data into knowledge of both developmental and stem cell biology. In the last several years, a new sub-discipline of computational stem cell biology has emerged that synthesizes the modeling of systems-level aspects of stem cells with high-throughput molecular data. In this review, we provide an overview of this new field and pay particular attention to the impact that single-cell transcriptomics is expected to have on our understanding of development and our ability to engineer cell fate.
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影响因子:
5.9
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通讯作者:
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