Sex-Specific Impacts of Exercise on Cardiovascular Remodeling.
Sex-Specific Impacts of Exercise on Cardiovascular Remodeling.
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DOI：
10.3390/jcm10173833
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发表时间：
2021-08-26
影响因子：
3.9
通讯作者：
Rahimian R
中科院分区：
文献类型：
--
作者：
Islam RA;Khalsa SSS;Vyas AK;Rahimian R
心血管疾病（CVD）仍然是男性和女性的主要死亡原因。生物性别在心血管生理学和病理性心血管重塑中发挥着重要作用。传统意义上的心血管病理性重构是指心肌梗死或高血压等损伤引起的分子、细胞和形态学改变。已知有规律的运动训练诱导生理性心血管重构和心血管装置的有益功能适应。然而，运动引起的心血管重构和功能适应的影响在男性和女性之间存在差异。本文旨在比较和对比运动诱导的心血管重构和功能适应的性别特异性表现。具体而言，我们综述了（1）心血管功能的性别差异，（2）生物性别对运动诱导的心血管重构和功能适应的影响，以及（3）不同类型，强度和持续时间的运动训练对心血管装置的性别特异性影响。该综述强调了动物和人类的研究，以提供一个全面的观点，运动引起的心血管系统的性别差异，并解决了在该领域的知识差距。
Cardiovascular diseases (CVD) remain the leading cause of death in men and women. Biological sex plays a major role in cardiovascular physiology and pathological cardiovascular remodeling. Traditionally, pathological remodeling of cardiovascular system refers to the molecular, cellular, and morphological changes that result from insults, such as myocardial infarction or hypertension. Regular exercise training is known to induce physiological cardiovascular remodeling and beneficial functional adaptation of the cardiovascular apparatus. However, impact of exercise-induced cardiovascular remodeling and functional adaptation varies between males and females. This review aims to compare and contrast sex-specific manifestations of exercise-induced cardiovascular remodeling and functional adaptation. Specifically, we review (1) sex disparities in cardiovascular function, (2) influence of biological sex on exercise-induced cardiovascular remodeling and functional adaptation, and (3) sex-specific impacts of various types, intensities, and durations of exercise training on cardiovascular apparatus. The review highlights both animal and human studies in order to give an all-encompassing view of the exercise-induced sex differences in cardiovascular system and addresses the gaps in knowledge in the field.
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DOI：
10.1007/978/-3-319-77932-4_21
发表时间：
2018-01-01
期刊：
SEX-SPECIFIC ANALYSIS OF CARDIOVASCULAR FUNCTION
影响因子：
--
作者：
Barnes, Jill N.;Fu, Qi
通讯作者：
Fu, Qi
DOI：
10.1152/ajpheart.01245.2006
发表时间：
2007-05-01
影响因子：
4.8
作者：
Botelho-Santos, Giancarla A.;Sampaio, Walkyria O.;dos Santos, Robson A. Souza
通讯作者：
dos Santos, Robson A. Souza
DOI：
10.1152/ajpregu.00358.2016
发表时间：
2017-02-01
影响因子：
2.8
作者：
Brown, Mary Beth;Neves, Evandro;Lahm, Tim
通讯作者：
Lahm, Tim
影响因子：
37.8
作者：
Adams, V;Linke, A;Hambrecht, R
通讯作者：
Hambrecht, R
影响因子：
8.2
作者：
Cassidy S;Thoma C;Hallsworth K;Parikh J;Hollingsworth KG;Taylor R;Jakovljevic DG;Trenell MI
通讯作者：
Trenell MI