Distribution of 203Hg in pregnant and fetal rats
Distribution of 203Hg in pregnant and fetal rats
复制标题
203Hg在孕鼠和胎鼠中的分布
DOI：
10.1002/tera.1420130306
复制
发表时间：
1976
期刊：
影响因子：
--
通讯作者：
T. Shepard
中科院分区：
文献类型：
--
作者：
R. B. King;M. Robkin;T. Shepard
The distribution of mercury was studied in pregnant and fetal rats after administration at days 11, 13, and 19 of pregnancy. Methyl-203Hg-chloride was used as a tracer to determine amounts of mercury in brain, kidneys, liver, heart, placenta, and whole fetus. The fetal brain was shown to accumulate 19 times more of the amount in the fetus than did the maternal brain the amount in the pregnant female. In addition, the fetal brain concentration was 3.4 times higher than the maternal brain concentration. Clearance studies showed that the organ concentrations were variable with little change occurring in maternal brain and fetus. These results are consistent with sensitivity to mercury damage being greater in the fetal than the maternal brain.
