Intrauterine growth retardation and premature delivery: The influence of maternal smoking and psychosocial factors
Intrauterine growth retardation and premature delivery: The influence of maternal smoking and psychosocial factors
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DOI：
10.2105/ajph.86.3.347
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发表时间：
1996-03-01
影响因子：
12.7
通讯作者：
Hemmingsen, R
中科院分区：
文献类型：
--
作者：
Nordentoft, M;Lou, HC;Hemmingsen, R
目标.本研究探讨了心理社会压力、母亲教育、社会支持、心理健康、饮酒和吸烟对胎儿宫内发育迟缓和早产的影响。在哥本哈根大学医院，2432名孕妇完成了一份关于一般健康、心理社会压力和社会人口特征的问卷。212例（8.7%）妇女早产。早产与心理社会压力（心理社会压力5分量表每增加1分，调整后的比值比[OR] = 1.14，整个量表为1.92）和学校教育水平差（7-9年学校教育的调整后OR = 2.62，10年为1.91，11-13年为1.0）相关。152例（6.3%）婴儿的出生体重低于第10百分位数。宫内发育迟缓与吸烟、每日饮酒、学校教育和社会网络变量有关。多元Logistic回归模型显示，宫内发育迟缓与吸烟习惯有关（调整后OR = 2.40，2.68，2.88，0-9支/天，10-15支/天，15支/天以上）。社会心理压力和有限的上学时间似乎影响早产。吸烟习惯影响胎儿宫内发育迟缓。
Objectives. This study investigated the influence of psychosocial stress, maternal schooling, social support, psychological well-being, alcohol, and smoking on intrauterine growth retardation and premature delivery.Methods. At a Copenhagen university hospital, 2432 pregnant women completed a questionnaire on general health, psychosocial stressors, and sociodemographic characteristics.Results. In 212 cases (8.7%) the women delivered prematurely. Preterm delivery was associated with psychosocial stress (adjusted odds ratio [OR] = 1.14 for each 1-point increase on the psychosocial stressor 5-point scale and 1.92 for the whole scale) and poor school education (adjusted OR = 2.62 for 7-9 years of schooling, 1.91 for 10 years, and 1.0 for 11-13 years). In 152 cases (6.3%), infants had a birthweight below the 10th percentile. Intrauterine growth retardation was associated with smoking, daily drinking, school education, and social network variables. In a multiple logistic regression model, intrauterine growth retardation was associated with smoking habits (adjusted OR = 2.40 for 0-9 cigarettes daily, 2.68 for 10-15 daily, and 2.88 for more than 15 daily).Conclusions. Psychosocial stressors and limited duration of schooling appeared to influence preterm delivery. Smoking habits influenced intrauterine growth retardation.