CODON USAGE IN PSEUDOMONAS-AERUGINOSA
CODON USAGE IN PSEUDOMONAS-AERUGINOSA
复制标题
DOI:
10.1093/nar/16.19.9323
复制
发表时间:
1988-10-11
影响因子:
14.9
通讯作者:
IGLEWSKI, BH
中科院分区:
文献类型:
--
作者:
WEST, SEH;IGLEWSKI, BH
We have generated a codonusage table for Pseudomonas aeruginosa. Codon usage in P. aeruginosa is extremely biased. In contrast to E. coli and yeast, P. aeruginosa preferentially uses those codons within a synonymous codon group with the strongest predicted codon-anticodon interaction. We were unable to correlate a particular codon usage pattern with predicted levels of mRNA expressively. The choice of a third base reflects the high guanine plus cytosine content of the P. aeruginosa genome (67.2%) and cytosine is the preferred nucleotide for the third codon position.