Health-related quality of life, fatigue and mood in patients with SLE and high levels of pain compared to controls and patients with low levels of pain

Health-related quality of life, fatigue and mood in patients with SLE and high levels of pain compared to controls and patients with low levels of pain
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DOI:
10.1177/0961203313502109
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发表时间:
2013-10-01
期刊:
影响因子:
2.6
通讯作者:
Henriksson, E. Welin
Henriksson, E. Welin
中科院分区:
医学4区
文献类型:
--
作者:
Waldheim, E.;Elkan, A-C;Henriksson, E. Welin

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目的探讨系统性红斑狼疮(SLE)疼痛程度高的患者的健康相关生活质量(HRQoL)、疲劳、焦虑和抑郁状况,并与疼痛程度低的患者和对照组进行比较。低痛组(76%,n=64,VAS 0- 39 mm)和高痛组(24%,n=20,VAS 40- 100 mm)。从一般人群中随机选择性别和年龄匹配的对照组。要求参与者完成关于自我报告疼痛、HRQoL、疲劳、焦虑和抑郁的问卷。结果高疼痛组的疲劳评分(中位数,36.5;四分位距(IQR),32.5-39.7)显著高于对照组(p
Objective The objective of this paper is to investigate health-related quality of life (HRQoL), fatigue, anxiety and depression in patients with systemic lupus erythematosus (SLE) and higher levels of pain and to compare them to patients with lower levels of pain and controls.Method Patients were dichotomized into two groups based on SLE-related pain score on the visual analog scale (VAS): low-pain group (76%, n=64, VAS 0-39mm) and high-pain group (24%, n=20, VAS 40-100mm). Sex- and age-matched controls were randomly selected from the general population. Participants were asked to complete questionnaires regarding self-reported pain, HRQoL, fatigue, anxiety and depression. Medical assessments also were recorded.Result Fatigue score in the high-pain group (median, 36.5; interquartile range (IQR), 32.5-39.7) was significantly higher (p