Synthesis of Novel Phosphoramidite Building Blocks from Pentaerythritol

Synthesis of Novel Phosphoramidite Building Blocks from Pentaerythritol
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由季戊四醇合成新型亚磷酰胺结构单元

DOI:
10.1055/s-2003-41406
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发表时间:
2003
期刊:
影响因子:
--
通讯作者:
B. Kim
B. Kim
中科院分区:
--
文献类型:
--
作者:
S. J. Kim;Eun‐Kyoung Bang;B. Kim

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以季戊四醇为原料,合成了四种含不同保护基团(DMTR、TBDMS、LEV)的亚磷酰胺。可以以正交方式选择性地解除对保护基团的保护。
The synthesis of four types of phosphoramidites containing various protecting groups (DMTr, TBDMS, Lev) has been achieved starting from pentaerythritol. The protecting groups can be deprotected selectively in an orthogonal manner.