The UK IBDQ - A British version of the inflammatory bowel disease questionnaire: development and validation

The UK IBDQ - A British version of the inflammatory bowel disease questionnaire: development and validation
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DOI:
10.1016/s0895-4356(99)00152-3
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发表时间:
2000-03-01
影响因子:
7.2
通讯作者:
Williams, JG
Williams, JG
中科院分区:
医学2区
文献类型:
--
作者:
Cheung, WY;Garratt, AM;Williams, JG

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健康相关生活质量(HRQL)的测量在炎症性肠病患者的研究中变得越来越重要。McMaster IBDQ是这些患者使用最广泛的HRQL仪器。然而,其在英国患者中的使用尚未得到验证。本研究开发并验证了英国版McMaster IBDQ(UK IBDQ)。英国IBDQ进行了测试,其可靠性,有效性,再现性和反应性与两个样本的患者。第一个样本包括180名参与随机临床试验的患者。第二组是从全国结肠炎和克罗恩病协会的成员中招募的。的分量表和英国IBDQ的总评分的可靠性证明了克朗巴赫的α和项目总相关。它们的有效性证明了它们与SF-36分量表和疾病活动的经验指数的相关性。良好的组内相关性和响应性比表明了其可重复性和响应性。研究结果支持英国IBDQ的可靠性,有效性,可重复性和反应性及其对英国患者的可接受性。(C)2000 Elsevier Science Inc. All rights reserved.
Measurement of health-related quality of life (HRQL) is becoming more important in studies of patients with inflammatory bowel disease. The McMaster IBDQ is the most widely used HRQL instrument for these patients. However, its use with patients in the United Kingdom has not been validated. This study develops and validates a UK version of the McMaster IBDQ (UK IBDQ). The UK IBDQ was tested with two samples of patients for its reliability, validity, reproducibility, and responsiveness. The first sample consisted of 180 patients participating in a randomized clinical trial. The second was recruited from members of the National Association for Colitis and Crohns Disease. Reliability of the subscales and the summary score of the UK IBDQ is demonstrated by Cronbach's alpha and item-total correlations. Their validity is demonstrated by their correlations with SF-36 subscales and an empirical index of disease activity. Good intraclass correlations and responsiveness ratios show their reproducibility and responsiveness. The findings support the reliability, validity, reproducibility, and responsiveness of the UK IBDQ and its acceptability to patients in UK. (C) 2000 Elsevier Science Inc. All rights reserved.