A meta-analytic review of prevalence for Brugada ECG patterns and the risk for death.
A meta-analytic review of prevalence for Brugada ECG patterns and the risk for death.
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Brugada 心电图模式患病率和死亡风险的荟萃分析综述
DOI：
10.1097/md.0000000000005643
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发表时间：
2016-12
期刊：
影响因子：
1.6
通讯作者：
Tang Q
中科院分区：
文献类型：
--
作者：
Quan XQ;Li S;Liu R;Zheng K;Wu XF;Tang Q
Brugada心电图模式（BrEP）在不同地区的患病率不同，其全球平均患病率未知。BrEP患者的死亡风险仍然未知。我们进行了一项荟萃分析，以确定BrEP的患病率和死亡风险比（RR）。纳入了2000年7月1日至2016年8月20日期间发表的相关研究，其中包含全因死亡和心源性死亡的患病率和RR。采用Meta分析的方法对患病率和RR进行分析。我们最终检索了24项关于BrEP患病率的研究和5项关于全因死亡和心源性死亡RR的研究。全世界溴化邻苯二甲酸的平均流行率为0.4%，亚洲最高（0.9%），北美最低（0.2%）。此外，男性的平均患病率为0.9%，而女性为0.1%。全因死亡的BrEP RR为0.78（95%置信区间0.45-1.37），心源性死亡的RR为0.92（95%置信区间0.23-3.66）。BrEP在全世界的流行率约为0.4%，在地区和性别上有不同的流行率。我们的研究表明，BrEP可能不能作为全因死亡和心源性死亡的预测因子。
The prevalence of Brugada ECG pattern (BrEP) is different in different regions, and its mean prevalence over the world is unknown. The risk of people with BrEP for death remains unknown. We performed a meta-analysis to determine the prevalence of BrEP and risk ratio (RR) for death. Relevant studies published between July 1, 2000 and August 20, 2016, which contain prevalence and RR for all-cause death and cardiac death, were included. The prevalence and RR are analyzed using meta-analysis. We finally retrieved 24 studies of the prevalence for BrEP and 5 studies of the RR for all-cause death and cardiac death. The worldwide mean prevalence of BrEP is 0.4%, with highest in Asia (0.9%) and lowest in North America (0.2%). Additionally, the mean prevalence in male is 0.9%, whereas it is 0.1% in female. The RR of BrEP for all-cause death is 0.78 (95% confidence interval 0.45–1.37), and for cardiac death it is 0.92 (95% confidence interval 0.23–3.66). The prevalence of BrEP is about 0.4% around the world with different prevalence in region and sex. Our study shows that BrEP may not be taken as a predictor of all-cause death and cardiac death.