Electronic Transport in Molecular Wires of Precisely Controlled Length Built from Modular Proteins.
Electronic Transport in Molecular Wires of Precisely Controlled Length Built from Modular Proteins.
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DOI：
10.1021/acsnano.1c10830
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发表时间：
2022-01-25
期刊：
影响因子：
17.1
通讯作者：
Lindsay, Stuart
中科院分区：
文献类型：
--
作者：
Zhang, Bintian;Ryan, Eathen;Wang, Xu;Song, Weisi;Lindsay, Stuart
关键词：
DNA分子线已经被广泛研究，因为它可以很容易地合成长度和组成可控的分子。蛋白质的情况并非如此。在这里，我们已经合成和研究了一系列的共识Tetratricopeptide Repeat（CTPR）的蛋白质，跨越4至20 nm的长度，在4 nm的增量。对于超过6 nm的长度，它们的电导超过了典型的分子线，oligo（phenylene-ethylenene），因为在蛋白质中电导随着长度的衰减更平缓。我们表明，虽然电导衰减符合指数（量子隧穿的特性），而不是线性增加的电阻与长度（跳跃运输的特性），它也占了长度的平方律依赖性（弱驱动跳跃的特性）。对衰变长度的能量依赖性的测量排除了量子隧穿的情况。载流子注入能量的共振表明蛋白质中的允许态与电极的费米能对齐。这些状态的能量和长距离的跳跃表明，空穴形成引起的重组在蛋白质内部大大减少。我们概述了一个计算蛋白质分子电子性质的模型。
DNA molecular wires have been studied extensively because of the ease with which molecules of controlled length and composition can be synthesized. The same has not been true for proteins. Here, we have synthesized and studied a series of Consensus Tetratricopeptide Repeat (CTPR) proteins, spanning 4 to 20 nm in length, in increments of 4 nm. For lengths in excess of 6 nm, their conductance exceeds that of the canonical molecular wire, oligo(phenylene-ethylenene), because of the more gradual decay of conductance with length in the protein. We show that, while the conductance decay fits an exponential (characteristic of quantum tunneling) and not a linear increase of resistance with length (characteristic of hopping transport), it is also accounted for by a square-law dependence on length (characteristic of weakly-driven hopping). Measurements of the energy dependence of the decay length rule out the quantum tunneling case. A resonance in the carrier injection energy shows that allowed states in the protein align with the Fermi energy of the electrodes. Both the energy of these states and the long-range of hopping suggest that the reorganization induced by hole formation is greatly reduced inside the protein. We outline a model for calculating the molecular-electronic properties of proteins.
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DOI：
10.1073/pnas.0508257102
发表时间：
2005-11-08
影响因子：
11.1
作者：
Chi, QJ;Farver, O;Ulstrup, J
通讯作者：
Ulstrup, J
影响因子：
16.6
作者：
Fereiro, Jerry A.;Kayser, Ben;Cahen, David
通讯作者：
Cahen, David
影响因子：
3.4
作者：
Aksimentiev, A;Schulten, K
通讯作者：
Schulten, K
影响因子：
10.8
作者：
Della Pia, Eduardo Antonio;Chi, Qijin;Elliott, Martin
通讯作者：
Elliott, Martin
影响因子：
6.7
作者：
Della Pia, Eduardo Antonio;Chi, Qijin;Elliott, Martin
通讯作者：
Elliott, Martin