Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment. Oncotarget.

Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment. Oncotarget.
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INPP4B 的缺失会通过 BRCA1、ATM 和 ATR 的缺失导致 DNA 修复缺陷,并且可以通过 PARP 抑制剂治疗来靶向。

DOI:
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发表时间:
2015
期刊:
影响因子:
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通讯作者:
Gewinner CA.
Gewinner CA.
中科院分区:
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文献类型:
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作者:
Ip LR;Poulogiannis G;Viciano FC;Sasaki J;Kofuji S;Spanswick VJ;Hochhauser D;Hartley JA;Sasaki T;Gewinner CA.

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