Impact of CYP2D6 and ADRB1 polymorphisms on heart rate of post-PCI patients treated with metoprolol.
Impact of CYP2D6 and ADRB1 polymorphisms on heart rate of post-PCI patients treated with metoprolol.
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DOI：
10.2217/pgs-2017-0203
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发表时间：
2024-05-31
期刊：
影响因子：
2.1
通讯作者：
Chen, Hui
中科院分区：
文献类型：
--
作者：
Gao, Xiaofeng;Wang, Huan;Chen, Hui
Aim: To explore the effect of CYP2D6*10 (100C>T) and ADRB1 1165 G>C polymorphisms on heart rate of post-PCI (percutaneous coronary intervention) patients treated with metoprolol succinate sustained-release tablets. Methods: A total of 756 inpatients with metoprolol succinate sustained-release tablets were selected and the genotypes of CYP2D6*10 and ADRB1 1165G>C were detected in 319 patients using gene chip detection. The target heart rate was defined as a resting heart rate
