Ionic Liquid of a Gold Nanocluster: A Versatile Matrix for Electrochemical Biosensors
Ionic Liquid of a Gold Nanocluster: A Versatile Matrix for Electrochemical Biosensors
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DOI：
10.1021/nn4053217
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发表时间：
2014-01-01
期刊：
影响因子：
17.1
通讯作者：
Lee, Dongil
中科院分区：
文献类型：
--
作者：
Kwak, Kyuju;Kumar, S. Senthil;Lee, Dongil
离子液体是室温熔融盐，其越来越多地用于电化学装置，例如电池、燃料电池和传感器，其中利用其固有的离子导电性。在这里，我们表明，结合阴离子，氧化还原活性Au-25簇与咪唑阳离子导致一个稳定的离子液体具有离子和电子导电性。发现Au-25离子液体可作为电流型酶生物传感器对葡萄糖检测的通用基质。在Au-25离子液体中引入葡萄糖氧化酶制备的酶电极具有较高的电催化活性和底物亲和性。发现电极中的Au-25簇作为有效的氧化还原介体以及决定检测灵敏度的电子导体。量子尺寸的金簇离子液体具有独特的电化学性质和几乎无限的结构可调性，可以作为多种电化学生物传感器的通用基质。
Ionic liquids are room-temperature molten salts that are increasingly used in electrochemical devices, such as batteries, fuel cells, and sensors, where their intrinsic ionic conductivity is exploited. Here we demonstrate that combining anionic, redox-active Au-25 clusters with imidazolium cations leads to a stable ionic liquid possessing both ionic and electronic conductivity. The Au-25 ionic liquid was found to act as a versatile matrix for amperometric enzyme biosensors toward the detection of glucose. Enzyme electrodes prepared by incorporating glucose oxidase in the Au-25 ionic liquid show high electrocatalytic activity and substrate affinity. Au-25 clusters in the electrode were found to act as effective redox mediators as well as electronic conductors determining the detection sensitivity. With the unique electrochemical properties and almost unlimited structural tunability, the ionic liquids of quantum-sized gold clusters may serve as versatile matrices for a variety of electrochemical biosensors.