Quantitative arthroscopic ultrasound evaluation of living human cartilage
Quantitative arthroscopic ultrasound evaluation of living human cartilage
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DOI：
10.1016/j.clinbiomech.2003.11.005
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发表时间：
2004-02-01
影响因子：
1.8
通讯作者：
Ikeuch, K
中科院分区：
文献类型：
--
作者：
Hattori, K;Takakura, Y;Ikeuch, K
客观的。为了研究是否可以通过一种新的诊断技术来定量评估活体人体关节软骨，该技术在关节镜下将超声波探头引入膝关节，然后通过小波变换分析A型回波图。设计。在关节镜下评估活体人类关节软骨的完整和受伤部位。小波图上选取最大幅度和回波持续时间（定义为包含95%回波信号的时间长度）作为定量指标。背景。原位关节软骨的定量评估有可能有助于我们了解软骨破坏和软骨再生的有效性。然而，尚未开发出一种可靠的定量软骨评估方法供临床使用。在关节镜下使用超声波探头分析活体人类关节软骨，并检查回波持续时间-最大幅度图上的软骨特征。结果。与人类尸体软骨数据的L形分布不同，活体人类关节软骨数据的分布在回波持续时间-最大幅度图上呈现出平滑的曲线，初始梯度陡峭，在回波持续时间的最高值处逐渐变平。结论。本研究提出了一种具有临床潜力的新的关节软骨定量评估系统。
Objective. To investigate whether living human articular cartilage can be evaluated quantitatively by means of a new diagnostic technique that introduces an ultrasonic probe into the knee joint under arthroscopy and then analyzes the A-mode echogram by means of wavelet transformation.Design. Intact and injured sites of living human articular cartilage were evaluated under arthroscopy. The maximum magnitude and the echo duration (defined as the length of time that included 95% of echo signal) were selected as the quantitative indices on the wavelet map.Background. Quantitative evaluation of articular cartilage in situ has the potential to contribute to our understanding of cartilage breakdown and to the effectiveness of cartilage regeneration. However, a reliable method of quantitative cartilage evaluation has yet to be developed for clinical use.Methods. Living human articular cartilage was analyzed using an ultrasonic probe under arthroscopy and the cartilage characteristics on the echo duration-maximum magnitude graph were examined.Results. Unlike the L-shape distribution of human cadaver cartilage data, the distribution of the living human articular cartilage data showed a smooth curve with a steep initial gradient that flattens gradually at the highest value of echo duration on the echo duration-maximum magnitude graph.Conclusions. The present Study suggests a new quantitative evaluation system for articular cartilage with clinical potential.