Corpus Callosum Section For Intractable Epilepsy
Corpus Callosum Section For Intractable Epilepsy
复制标题
胼胝体切片治疗顽固性癫痫
DOI：
10.1007/978-1-4613-2419-5_10
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
P. Williamson
中科院分区：
文献类型：
--
作者：
P. Williamson;P. Williamson
1940年首次报道了胼胝体分离术治疗顽固性癫痫（货车Wagenen和Herren，1940）。这个原始系列中包含的患者的确切数量一直不清楚，但可能多达27人。前10例病例报告较为详细，但随访数据有限。随后的病例是几项心理学研究的主题，但没有更多的临床信息。在20世纪60年代，当Bogen和他的同事开始报道他们的系列结果时，对胼胝体部分的兴趣重新恢复（Bogen和Vogel，1962，1965，1975; Bogen等人，1969; Gordonet等人，1971年）。临床资料和随访12例，但大多数注意力是针对胼胝体切片的神经心理后果。在此之后，有几篇关于胼胝体部分用于癫痫控制的报道（Luessenhop，1970; Luessenhop等人，1970），但直到达特茅斯系列的最初报告才获得临床癫痫发作模式的详细分析和长期随访数据（Wilsonet al.，1975年）。随后，有一系列文章记录了达特茅斯项目经验的逐步积累（Wilsonet al.，1977年，1978年）。这在最近一篇描述20名患者的文章中达到高潮，该文章是在威尔逊博士不幸去世后发表的（Wilsonet al.，1982年）。虽然达特茅斯系列代表了第一个全面的努力，记录胼胝体部分癫痫控制的疗效，数字仍然很小，最佳的选择标准尚未确定。
Division of the corpus callosum for intractable epilepsy was first reported in 1940 (Van Wagenen and Herren, 1940). The exact number of patients included in this original series has never been clear, but it may have been as many as 27. The first ten cases were reported in some detail, but followup data were limited. Subsequent cases were the subject of several psychological studies, but additional clinical information is not available. Interest in callosal section was revived in the 1960s when Bogen and his colleagues began to report the results of their series (Bogen and Vogel, 1962, 1965, 1975; Bogenet al., 1969; Gordonet al., 1971). Clinical data and followup were given for 12 cases, but most attention was directed to the neuropsychological consequences of callosal sectioning. Following this there were several reports concerning the use of callosal section for epilepsy control (Luessenhop, 1970; Luessenhopet al., 1970), but it was not until the initial report from the Dartmouth series that detailed analysis of clinical seizure patterns and prolonged followup data became available (Wilsonet al., 1975). Subsequently there have been a series of articles documenting the progressive accumulation of experience from the Dartmouth program (Wilsonet al., 1977, 1978). This culminated in a recent article describing 20 patients published just after Dr. Wilson’s unfortunate death (Wilsonet al., 1982). Although the Dartmouth series represents the first comprehensive effort at documenting the efficacy of corpus callosal section on seizure control, the numbers remain small and the optimum selection criteria have yet to be determined.