Effects of early postfiltration ocular hypotony on visual acuity, long-term intraocular pressure control, and posterior segment morphology
Effects of early postfiltration ocular hypotony on visual acuity, long-term intraocular pressure control, and posterior segment morphology
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DOI：
10.1097/00061198-200104000-00003
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发表时间：
2001-04-01
影响因子：
2
通讯作者：
Pfeiffer, N
中科院分区：
文献类型：
--
作者：
Schwenn, O;Kersten, I;Pfeiffer, N
目的：探讨滤过术后低眼压对视力和降低眼压的影响。患者和方法：我们前瞻性研究43例小梁切除术患者的43只眼，未使用抗代谢物12个月。结果：术后最低IOP值为4.9 +/- 3.6 mm Hg（范围：0-14 mm PIE）。与术后6周（P = 0.016）、6个月（P = 0.009）、1年（P = 0.027） IOP有统计学意义。术后6周视力恶化的眼术后低眼压较强（与术后最低IOP相关，P = 0.035）。IOP小于5mmhg的平均周期为3.5±8.0天，IOP小于10mmhg的平均周期为45.4±68.8天（范围0 ~ 276天）。介绍了一种基于IOP和低眼压持续时间的低眼压评分方法。在6个月的随访中，低眼压的形态学症状（如微小的视网膜皱襞）与低眼压持续时间（P = 0.029）和低眼压评分（P = 0.001）之间存在相关性。结论：滤过术后低眼压可导致术后早期视力下降。相反，术后早期低眼压与较好的长期IOP控制相关。6个月后对视力无不良影响。
Purpose: To determine whether hypotony after filtration surgery has any influence on visual acuity and intraocular pressure (IOP) lowering.Patients and Methods: We prospectively investigated 43 eyes of 43 patients undergoing trabeculectomy without the use of antimetabolites for 12 months.Results: The lowest postoperative IOP valued 4.9 +/- 3.6 mm Hg (range, 0-14 mm PIE). It correlated statistically significant with the IOP 6 weeks (P = 0.016), 6 months (P = 0.009), and 1 year after surgery (P = 0.027). Eyes with a deterioration of visual acuity 6 weeks after surgery had undergone a stronger postoperative hypotony (correlation with lowest postoperative IOP, P = 0.035).The mean period with an IOP less than 5 mm Hg was 3.5 +/- 8.0 days, and the mean period with an IOP less than 10 mm Hg lasted 45.4 +/- 68.8 days (range, 0-276 days). A hypotony score based on IOP and duration of hypotony was introduced. A correlation was detected between morphologic signs of hypotony, such as tiny retinal folds, at the 6-month follow-up and the duration of hypotony (P = 0.029) and hypotony score (P = 0.001).Conclusions: Hypotony after filtration surgery may decrease visual acuity in the early postoperative period. Conversely, early postoperative hypotony correlated with better long term IOP control. There was no deleterious effect on visual acuity after 6 months.