Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4
Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4
复制标题
烟草相关口腔癌的同基因动物模型揭示了原位抗 CTLA-4 的活性
DOI：
10.1038/s41467-019-13471-0
复制
发表时间：
2019-12-05
影响因子：
16.6
通讯作者：
Gutkind, J. Silvio
中科院分区：
文献类型：
--
作者：
Wang, Zhiyong;Wu, Victoria H.;Gutkind, J. Silvio
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. Tobacco use is the main risk factor for HNSCC, and tobacco-associated HNSCCs have poor prognosis and response to available treatments. Recently approved anti-PD-1 immune checkpoint inhibitors showed limited activity (
