Levels and profiles of PCDDs, PCDFs and cPCBs in Belgian breast milk. Estimation of infant intake
Levels and profiles of PCDDs, PCDFs and cPCBs in Belgian breast milk. Estimation of infant intake
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DOI：
10.1016/s0045-6535(02)00140-6
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发表时间：
2002-09-01
期刊：
影响因子：
8.8
通讯作者：
De Pauw, E
中科院分区：
文献类型：
--
作者：
Focant, JF;Pirard, C;De Pauw, E
多氯二苯并对二恶英（PCDDs），多氯二苯并呋喃（PCDFs）和非邻位（共面）多氯联苯（cPCBs）的特定同源物的分析进行了20个非合并母乳样本收集或接近瓦隆（比利时）的工业区。多氯二苯并对二恶英和多氯二苯并呋喃的浓度范围为16.0至52.1皮克毒性当量/克脂肪，平均值为29.4皮克毒性当量/克脂肪。如果将共面多氯联苯（77、126、169）纳入毒性当量计算，其含量范围为22.2至100.2皮克毒性当量/克脂肪，平均值为40.8皮克毒性当量/克脂肪。看来2，3，7，8-四氯二苯并对二恶英、1，2，3，7，8-五氯二苯并对二恶英、2，3，4，7，8-五氯二苯并呋喃和多氯联苯-126占毒性当量的90%以上。多氯二苯并对二恶英和多氯二苯并呋喃的膳食摄入量估计为76皮克毒性当量/千克体重/天。这一数值几乎是世界卫生组织规定的每日可耐受摄入量的20倍。103皮克毒性当量/千克体重/天的数值代表多氯二苯并对二恶英、多氯二苯并呋喃和商用多氯联苯的摄入量（不包括单邻位多氯联苯）。(C)2002年由Elsevier Science Ltd.出版
Congener-specific analyses of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and non-ortho (coplanar) polychlorinated biphenyls (cPCBs) were performed on 20 non-pooled breast milk samples collected in or close to an industrial area of Wallonia (Belgium). PCDD/F concentrations ranged between 16.0 and 52.1 pg TEQ/g fat, with a mean value of 29.4 pg TEQ/g fat. If coplanar PCBs (77, 126, 169) are included in TEQ calculations, levels ranged between 22.2 and 100.2 pg TEQ/g fat, with a mean value of 40.8 pg TEQ/g fat. It appears that 2,3,7,8-TCDD, 1,2,3,7,8-PeCDD, 2,3,4,7,8-PeCDF and PCB-126 account for more than 90% of the TEQ. Estimated PCDD/F dietary intake is 76 pg TEQ/kg body weight (bw)/day. This value is almost 20 times higher than the World Health Organization tolerable daily intake. A value of 103 pg TEQ/kg bw/day represents the intake of PCDDs, PCDFs and cPCBs (no mono-ortho PCBs included). (C) 2002 Published by Elsevier Science Ltd.