A structural basis for Hering's law: projections to extraocular motoneurons.
A structural basis for Hering's law: projections to extraocular motoneurons.
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赫林定律的结构基础：眼外运动神经元的投影。
DOI：
10.1126/science.2343316
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Highstein,SM
中科院分区：
文献类型：
--
作者：
Moschovakis,AK;Scudder,CA;Highstein,SM
眼球共轭运动是通过同时激活双眼的几块肌肉来完成的。这种协同肌肉激活背后的神经机制一直是大量实验和争论的问题。为了探讨这一问题，我们研究了一类灵长类动物运动前神经元细胞的投射，即驱动垂直快速眼动的垂直中铅爆发神经元（VMLBs）。向上的VMLBs轴突在运动神经元池内双侧分支，供应双眼上直肌和下斜肌。向下的VMLBs轴突在动眼核下直肌部分和滑车核内同侧分叉。因此，在共轭垂直快速眼动过程中，VMLBs可以驱动双眼的垂直运动神经元池；这些数据支持赫林定律。
Conjugate eye movements are executed through the concurrent activation of several muscles in both eyes. The neural mechanisms that underlie such synergistic muscle activations have been a matter of considerable experimentation and debate. In order to investigate this issue, the projections of a class of primate premotoneuronal cells were studied, namely, the vertical medium-lead burst neurons (VMLBs), which drive vertical rapid eye movements. Axons of upward VMLBs ramify bilaterally within motoneuron pools that supply the superior rectus and inferior oblique muscles of both eyes. Axons of downward VMLBs ramify ipsilaterally in the inferior rectus portion of the oculomotor nucleus and in the trochlear nucleus. Thus, VMLBs can drive vertical motoneuron pools of both eyes during conjugate vertical rapid eye movements; these data support Hering's law.