Application of Ruthenium Complexes of Triazole-Containing Tridentate Ligands to Asymmetric Transfer Hydrogenation of Ketones
Application of Ruthenium Complexes of Triazole-Containing Tridentate Ligands to Asymmetric Transfer Hydrogenation of Ketones
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DOI：
10.1021/ol302354z
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发表时间：
2012-10-19
期刊：
影响因子：
5.2
通讯作者：
Wills, Martin
中科院分区：
文献类型：
--
作者：
Johnson, Tarn C.;Totty, William G.;Wills, Martin
The synthesis of a series of tridentate ligands based on a homochiral 1,2-diamine structure attached to a triazole group and their subsequent applications to the asymmetric transfer hydrogenation of ketones are described. In the best cases, alcohols of up to 93% ee were obtained. Although base is not required, the use of Ru-3(CO)(12) as metal source is essential, indicating a unique mechanism for the formation of the active catalyst.
