Bioactive pterocarpans from Trigonella foenum-graecum L
Bioactive pterocarpans from Trigonella foenum-graecum L
复制标题
胡芦巴中的生物活性紫檀素
DOI：
10.1016/j.foodchem.2019.126092
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发表时间：
2020
期刊：
影响因子：
8.8
通讯作者：
Jianqing Yu
中科院分区：
文献类型：
--
作者：
Zi Wu;You-Sheng Cai;Ruiying Yuan;Qian Wan;Di Xiao;Jiachuan Lei;Jianqing Yu
生长foenum-graecumL。胡芦巴（葫芦巴）在中国和北非国家被用作叶菜和香料。然而，其空中部分的生化成分很少被探索。本研究对该可食植物地上部位的不同提取部位的生物活性进行了评价，发现乙酸乙酯提取部位具有较强的抗氧化和抗炎作用。通过生物测定法分离得到1个新化合物(1)和12个已知化合物（2-13），其中9个（5-13）为首次在胡芦巴中报道，4个（9,11 - 13）具有较强的抗氧化活性，11个（1 - 3,5 - 12）具有明显的抗炎活性。本研究表明，翼龙素是这种可食用植物的主要活性成分。除了作为食物的营养价值外，该植物的空中部分还可以进一步开发为食品工业中的功能性食品或抗氧化剂。
Trigonella foenum-graecumL. (fenugreek) is used as a leafy vegetable and spice in China and North African countries. However, the biochemical components of its aerial parts were rarely explored. In this study, the bioactivities of the various extract fractions from the aerial parts of this edible plant were assessed, the ethyl acetate extract fraction exhibited strong antioxidant and anti-inflammatory effects. Through bioassay-guided isolation, one new pterocarpan (1), as well as twelve known pterocarpans (2–13) were obtained, nine of them (5–13) were first reported in the fenugreek, four pterocarpans (9,11–13) had strong antioxidant activity, eleven pterocarpans (1–3,5–12) possessed obvious anti-inflammatory activity. This study indicates that pterocarpans are main bioactive components of this edible plant. Apart from its nutritional value as food, the aerial parts of this plant can also be further explored as functional foods or antioxidants in food industry.