A Comparative Study of Chest Computed Tomography Features in Young and Older Adults With Corona Virus Disease (COVID-19)
A Comparative Study of Chest Computed Tomography Features in Young and Older Adults With Corona Virus Disease (COVID-19)
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DOI：
10.1097/rti.0000000000000513
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发表时间：
2020-07-01
影响因子：
3.3
通讯作者：
Xia, Liming
中科院分区：
文献类型：
--
作者：
Zhu, Tingting;Wang, Yujin;Xia, Liming
目的：分析60岁及以下新冠状病毒肺炎患者和60岁以上老年人肺炎最常见的CT表现。材料和方法：回顾分析72例有症状的新冠肺炎患者的胸部CT表现，其中青年组44例，年龄47.5+/-8.7岁；老年组28例，年龄68.4+/-6.0岁。CT表现包括密度(纯毛玻璃影、毛玻璃影合并实变、实变)、累及的肺叶数目、病变分布及主要伴随征象进行分析和比较。结果：特征性CT表现为双侧肺叶广泛受累，周围可见磨玻璃样、磨玻璃样实变，有时伴有小叶间隔增厚、胸膜下线和胸膜增厚。老年组肺叶广泛受累比例较高(71.4%比36.4%，P=0.009)，胸膜下线和胸膜增厚的发生率较高(分别为50.0%比25.0%和71.4%比40.9%，P=0.030和0.011)。结论：老年和青年冠状病毒病患者有一些共同的CT表现，但老年患者更容易出现广泛的肺叶受累、胸膜下线条和胸膜增厚。这些分化特征可能与疾病的进展和预后有关。
Objective: To analyze the most common computed tomography (CT) findings of pneumonia caused by new coronavirus in younger patients (60 and younger) and older adults (older than 60). Materials and Methods: The chest CT images of 72 symptomatic patients with corona virus disease (COVID-19) were analyzed retrospectively, including 44 younger patients (47.5 +/- 8.7 y old) and 28 older patients (68.4 +/- 6.0 y old). CT findings including density (pure ground-glass opacities, ground-glass opacities with consolidation, consolidation), the number of lobes involved, lesion distribution, and the main accompanying signs were analyzed and compared. Results: Characteristic CT findings included the lobes of bilateral lung extensively involved, ground-glass opacity and ground-glass opacity with consolidation in the peripheral area, sometimes accompanied by interlobular septal thickening, and subpleural line and pleural thickening. Compared with the younger group, the proportion of extensive involvement of lung lobes was higher in the elderly group (71.4% vs. 36.4%,P=0.009), and subpleural line and pleural thickening were more likely to occur (50.0% vs. 25.0%, and 71.4% vs. 40.9%,P=0.030 and 0.011, respectively). Conclusion: Elderly and younger patients with corona virus disease have some common CT features, but older patients are more likely to have extensive lung lobe involvement, and subpleural line and pleural thickening. These differentiated characteristics may be related to the progress and prognosis of the disease.