MONOCLONAL-ANTIBODY TO CYTOKERATIN FOR USE IN ROUTINE HISTOPATHOLOGY
MONOCLONAL-ANTIBODY TO CYTOKERATIN FOR USE IN ROUTINE HISTOPATHOLOGY
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DOI：
10.1136/jcp.37.9.975
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发表时间：
1984-01-01
影响因子：
3.4
通讯作者：
BODMER, WF
中科院分区：
文献类型：
--
作者：
MAKIN, CA;BOBROW, LG;BODMER, WF
CAM 5.2是一种鼠单克隆抗体，针对[人]结肠癌细胞系HT 29产生，其识别分泌上皮内的低分子量细胞内细胞角蛋白。广泛的间接免疫组织化学研究证实，这种抗体染色福尔马林固定（和新鲜冷冻）正常和恶性人体组织以一致的方式。常规处理的病理组织的可靠染色提供了人类恶性上皮疾病的更准确的鉴定和分期。
CAM 5.2 is a murine monoclonal antibody, raised against the [human] colon carcinoma cell line HT29, which recognizes lower molecular weight intracellular cytokeratin proteins within secretory epithelia. Extensive indirect immunohistochemical studies have confirmed that this antibody stains formalin fixed (and freshly frozen) normal and malignant human tissue in a consistent manner. Reliable staining of conventionally processed pathological tissues provides more accurate identification and staging of human malignant epithelial diseases.