Primary pulmonary vein stenosis among premature infants with single-vessel disease.
Primary pulmonary vein stenosis among premature infants with single-vessel disease.
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DOI：
10.1038/s41372-020-00830-9
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发表时间：
2021-07
期刊：
影响因子：
--
通讯作者：
Backes CH
中科院分区：
文献类型：
--
作者：
Zettler E;Rivera BK;Stiver C;Boe B;Cua C;Ball MK;Smith CV;Slaughter JL;Chen B;Callahan R;Backes CH
描述诊断为单支原发性肺静脉狭窄（PPVS）的早产儿最初采用保守治疗（主动监测并延迟治疗）的结局。一项在妊娠<37周的婴儿中进行的单血管PPVS回顾性队列研究（2009-2019年）。婴儿分为2类：疾病进展和疾病稳定。检查心脏病结局，并进行Kaplan-Meier生存分析。其中包括20名婴儿。与稳定组相比（0/10，0%），进展组所有婴儿至少有重度狭窄或闭锁（10/10，100%; P<0.01）。诊断时重度肺动脉高压在进展组（5/10，50%）比稳定组（0/10，0%; P=0.03）增加。进展组婴儿的存活率低于稳定组（Log-Rank检验，P<0.01）。在患有单血管PPVS的早产儿中，可以进行风险分层，其中可以应用更有针对性的个体化治疗。
Describe outcomes among preterm infants diagnosed with single-vessel primary pulmonary vein stenosis (PPVS) initially treated using conservative management (active surveillance with deferral of treatment). Retrospective cohort study at a single, tertiary-center (2009-2019) among infants <37 weeks’ gestation with single-vessel PPVS. Infants were classified into 2 categories: disease progression and disease stabilization. Cardiopulmonary outcomes were examined, and a Kaplan-Meier survival analysis performed. Twenty infants were included. Compared to infants in the stable group (0/10, 0%), all infants in the progressive group had development of at least severe stenosis or atresia (10/10, 100%; P<0.01). Severe pulmonary hypertension at diagnosis was increased in the progressive (5/10, 50%) than the stable group (0/10, 0%; P=0.03). Survival was lower among infants in the progressive than the stable group (Log-Rank Test, P<0.01). Among preterm infants with single-vessel PPVS, risk stratification may be possible, wherein more targeted, individualized therapies could be applied.
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影响因子：
5.1
作者：
Krishnan, Usha;Feinstein, Jeffrey A.;Abman, Steven H.
通讯作者：
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影响因子：
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作者：
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Backes, Carl H.
DOI：
10.1016/j.jtcvs.2019.08.105
发表时间：
2020-03-01
影响因子：
6
作者：
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通讯作者：
Alsoufi, Bahaaldin
影响因子：
4.6
作者：
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通讯作者：
Lacour-Gayet, Francois
DOI：
10.1016/j.jpeds.2017.03.027
发表时间：
2017-07
期刊：
The Journal of pediatrics
影响因子：
--
作者：
Carlton EF;Sontag MK;Younoszai A;DiMaria MV;Miller JI;Poindexter BB;Abman SH;Mourani PM
通讯作者：
Mourani PM