Presence of Antibiotics in Shallow Groundwater in the Northern and Southwestern Regions of China
Presence of Antibiotics in Shallow Groundwater in the Northern and Southwestern Regions of China
复制标题
中国北部和西南地区浅层地下水中抗生素的存在
DOI：
10.1111/gwat.12596
复制
发表时间：
2018-05-01
期刊：
影响因子：
2.6
通讯作者：
Yan, Tao
中科院分区：
文献类型：
--
作者：
Chen, Liang;Lang, Hang;Yan, Tao
抗生素被广泛使用，其对环境和人类健康的不利影响引起了人们的严重关注。据我们所知，在这项工作之前，尽管有大量的猜测，但没有证据表明中国的地下水中可能存在抗生素。本文报道了中国北部和西南部浅层地下水中氯霉素、林可西胺、大豆内酯、喹诺酮类、磺胺类和四环素类共6类35种靶标抗生素的检测结果。在地下水样本中检测到35种目标抗生素中的34种；在74口监测井中有73口含有至少一种抗生素；在74口井中有72口至少检测到两种抗生素。在高浓度下检出氧氟沙星(1199.7 ng/L)、林可霉素(860.7 ng/L)、诺氟沙星(441.9 ng/L)以及磺胺吡啶(70%)、诺氟沙星(69%)、林可霉素(%)等检出频率最高的抗生素。在这些地下水样品中，林可酰胺的检出频率和浓度最高，但没有观察到6种抗生素的明显分布规律。此外，中国西南部的浅层地下水似乎含有大部分抗生素，这可能是由于抗生素排放量高，地下水与地表基质交换频繁所致。这项工作的发现表明，中国的地下水受到了广泛的抗生素污染，可能还有其他迄今尚未调查的药物化合物。
Antibiotics are widely used, and there is a serious concern about its adverse impacts on the environment and human health. To our knowledge, prior to this work, there was no evidence of the potential presence of antibiotics in groundwater in China, despite populous speculations. This study reported the detection of 35 target antibiotics of 6 groups (chloramphenicois, lincosamides, marcrolides, quinolones, sulfonamides, and tetracyclines), in shallow groundwater samples collected in northern and southwestern China. Thirty‐four of thirty‐five target antibiotics were detected in the groundwater samples; 73 of 74 monitoring wells contained at least one antibiotic; and at least two antibiotics were detected in 72 of the 74 wells. Ofloxacin (1199.7 ng/L), lincomycin (860.7 ng/L), and norfloxacin (441.9 ng/L) as well as antibiotics with the highest detection frequency such as sulfapyridine (70%), norfloxacin (69%), and lincomycin (64%) were detected at elevated concentrations. The highest detection frequency and concentration of lincosamides were observed in those groundwater samples, but no clear distribution patterns were observed for the six antibiotic groups. Moreover, shallow groundwater in southwestern China seemed to contain most antibiotics, likely due to the high antibiotics discharge and frequent exchange of groundwater with surface matrices. The findings from this work suggest that groundwater in China has been widely contaminated by antibiotics, and presumably other pharmaceutical compounds that have not been investigated to date.