Selective C(70) encapsulation by a robust octameric nanospheroid held together by 48 cooperative hydrogen bonds.
Selective C(70) encapsulation by a robust octameric nanospheroid held together by 48 cooperative hydrogen bonds.
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DOI：
10.1038/ncomms15109
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发表时间：
2017-05-10
影响因子：
16.6
通讯作者：
Stefankiewicz AR
中科院分区：
文献类型：
--
作者：
Markiewicz G;Jenczak A;Kołodziejski M;Holstein JJ;Sanders JKM;Stefankiewicz AR
通过氢键将多个结构单元自组装成具有选择性结合功能的明确定义的纳米结构仍然是超分子化学中最重要的挑战之一。在这里，我们报告的对映体纯nanocaptants的发现，形成通过自组装的8个氨基酸功能化的分子在非极性溶剂中通过48个氢键。纳米胶囊是非常稳健的，在低温和高温下稳定，并在碱的存在下，大概是由于氢键基序的合作几何形状。由于小的孔径、大的内腔和足够的动态性，纳米胶囊能够识别和封装大的芳香族客体，如富勒烯C60和C70。主体与C70之间的结构和电子互补性导致其从C60和C70的混合物中优先和选择性地结合。单个氢键很弱，因此通过氢键自组装多个组件是一个重大挑战。在这里，作者报告了一种由48个合作氢键结合在一起的稳健的对映体纯纳米胶囊，并将其用于C70的选择性结合。
Self-assembly of multiple building blocks via hydrogen bonds into well-defined nanoconstructs with selective binding function remains one of the foremost challenges in supramolecular chemistry. Here, we report the discovery of a enantiopure nanocapsule that is formed through the self-assembly of eight amino acid functionalised molecules in nonpolar solvents through 48 hydrogen bonds. The nanocapsule is remarkably robust, being stable at low and high temperatures, and in the presence of base, presumably due to the co-operative geometry of the hydrogen bonding motif. Thanks to small pore sizes, large internal cavity and sufficient dynamicity, the nanocapsule is able to recognize and encapsulate large aromatic guests such as fullerenes C60 and C70. The structural and electronic complementary between the host and C70 leads to its preferential and selective binding from a mixture of C60 and C70. Individual hydrogen bonds are weak, so self-assembling multiple components via hydrogen bonding is a significant challenge. Here the authors report a robust, enantiopure nanocapsule held together by 48 cooperative hydrogen bonds, and use it for the selective binding of C70.