Nature's Clocks and Human Mood: The Circadian System Modulates Reward Motivation
Nature's Clocks and Human Mood: The Circadian System Modulates Reward Motivation
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DOI：
10.1037/a0017080
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发表时间：
2009-10-01
期刊：
影响因子：
4.2
通讯作者：
Trinder, John
中科院分区：
文献类型：
--
作者：
Murray, Greg;Carrington, Melinda J.;Trinder, John
现有的文献奖励动机很少注意到这样一个事实，即奖励潜力的环境变化显着的光/暗周期。相比之下，进化论非常严肃地对待这一事实：在所有物种中，昼夜节律系统都是为了优化环境参与的日常节奏而调整的。我们使用了3个标准协议来证明，人类的奖励动机，积极影响（PA）的动态测量，是由生物钟内源性调制。在自然条件下，13.0%的PA方差解释了24小时的正弦曲线。在恒定的常规方案中，25.0%的PA差异可以通过核心体温（CBT）中未掩盖的昼夜节律来解释。一项强制性的研究表明，PA与CBT在表现出独立于28小时睡眠/觉醒周期的昼夜节律周期方面保持一致。它的结论是昼夜节律系统调制奖励激活，并讨论了正常和异常情绪的模型的影响。
Existing literature on reward motivation pays scant attention to the fact that reward potential of the environment varies dramatically with the light/dark cycle. Evolution, by contrast, treats this fact very seriously: In all species, the circadian system is adapted to optimize the daily rhythm of environmental engagement. We used 3 standard protocols to demonstrate that human reward motivation, as measured in the dynamics of positive affect (PA), is modulated endogenously by the circadian clock. Under naturalistic conditions, 13.0% of PA variance was explained by a 24-hr sinusoid. In a constant routine protocol, 25.0% of PA variance was explained by the unmasked circadian rhythm in core body temperature (CBT). A forced desynchrony study showed PA to align with CBT in exhibiting circadian periodicity independent of a 28-hr sleep/wake cycle. It is concluded that the circadian system modulates reward activation, and implications for models of normal and abnormal mood are discussed.