Medical management of urinary stone disease
Medical management of urinary stone disease
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DOI：
10.1159/000080252
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发表时间：
2004-01-01
影响因子：
--
通讯作者：
Pak, CYC
中科院分区：
文献类型：
--
作者：
Pak, CYC
各种饮食和代谢因素可能有助于或导致特发性草酸钙肾结石的结石形成。饮食因素包括动物蛋白、草酸盐和钠的高摄入量，以及液体和含钾柑橘类产品的低摄入量。结石的一些代谢原因是高钙尿、低柠檬酸尿、痛风素质、高尿酸尿和高尿酸尿。所有结石患者都应进行饮食调整，包括高液体摄入量、限制草酸盐和钠的摄入量、动物蛋白均衡饮食，并补充足够的水果和蔬菜摄入量。当饮食调整对控制结石形成无效或存在严重代谢紊乱时，可能需要药物干预。在一个简单的方法中，噻嗪或吲达帕胺与柠檬酸钾被推荐用于高钙尿患者，而柠檬酸钾单独用于其余正常钙尿受试者。版权所有（C）2004 S. Karger AG，巴塞尔。
A variety of dietary and metabolic factors may contribute or cause stone formation in idiopathic calcium oxalate nephrolithiasis. Dietary factors include a high intake of animal proteins, oxalate and sodium, and a low intake of fluids and potassium-containing citrus products. Some of the metabolic causes of stones are hypercalciuria, hypocitraturia, gouty diathesis, hyperoxaluria, and hyperuricosuria. Dietary modification, to be applied in all patients with stones includes a high fluid intake, restriction of oxalate and sodium, and balanced diet with animal proteins complemented by adequate intake of fruits and vegetables. When dietary modification is ineffective in controlling stone formation or in the presence of severe metabolic derangements, a pharmacologic intervention may be necessary. In a simple approach, thiazide or indapamide with potassium citrate is recommended for patients with hypercalciuria, and potassium citrate alone for the remaining normocalciuric subjects. Copyright (C) 2004 S. Karger AG, Basel.