The efficacy and toxicity of VAD in the treatment of myeloma and related disorders.

The efficacy and toxicity of VAD in the treatment of myeloma and related disorders.
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VAD 在治疗骨髓瘤及相关疾病中的功效和毒性。

DOI:
10.1111/j.1600-0609.1986.tb02632.x
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发表时间:
2009
期刊:
Scandinavian journal of haematology
影响因子:
--
通讯作者:
A. Parker
A. Parker
中科院分区:
--
文献类型:
--
作者:
T. Sheehan;M. Judge;A. Parker

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最近报道了29例晚期难治性骨髓瘤患者接受4-d阿曲库铵和阿霉素(VAD)输注治疗的令人印象深刻的结果。我们报告了我们自己的经验与此协议在13例骨髓瘤和相关的淋巴组织增生性疾病。在其中2例病例中,VAD被用作一线治疗。三分之二的病例出现了客观反应,治疗的主要并发症是感染,主要是细菌性感染。
Impressive results have recently been reported in 29 cases of advanced refractory myeloma treated with 4-d infusions of Vincristine and Adriamycin (VAD). We report our own experience with this protocol in 13 cases of myeloma and related lymphoproliferative disorders. In 2 of these cases, VAD was used as first line treatment. Objective responses were seen in two-thirds of cases and the major complication of therapy was infection, predominantly bacterial in nature.
DOI: 10.1056/nejm198405243102104
发表时间: 1984-01-01
影响因子: 158.5
作者:
BARLOGIE, B;SMITH, L;ALEXANIAN, R
通讯作者: ALEXANIAN, R