Family disruption in childhood and risk of adult depression
Family disruption in childhood and risk of adult depression
复制标题
DOI：
10.1176/appi.ajp.160.5.939
复制
发表时间：
2003-05-01
影响因子：
17.7
通讯作者：
Buka, SL
中科院分区：
文献类型：
--
作者：
Gilman, SE;Kawachi, I;Buka, SL
目的：作者研究了儿童早期家庭破裂和低社会经济地位对成年期重性抑郁症发病的影响。方法：参与者是1104名在罗德岛州普罗维登斯（Providence）的全国围产期合作项目中怀孕期间登记的母亲的后代。在出生前和7岁时获得儿童家庭破裂和社会经济地位的测量。采用结构化诊断访谈来评估受访者在18岁至39岁之间的重度抑郁症发作史。生存分析用于确定儿童时期抑郁症发病的风险。结果：无论是母亲未再婚还是母亲再婚的研究对象，在童年早期父母离婚与他们一生中患抑郁症的风险较高有关。这些影响在父母冲突严重的情况下更为明显。与被调查者成年后的社会经济地位无关，儿童时期的低社会经济地位预示着抑郁风险的增加。结论：儿童早期家庭破裂和低社会经济地位增加了重度抑郁症的长期风险。减少儿童时期的不利条件可能是预防抑郁症的一种途径。需要确定将幼儿环境的各个方面与成人心理健康联系起来的可改变的途径，以减轻儿童不利条件的长期后果。
Objective: The authors examined the risk that family disruption and low socioeconomic status in early childhood confer on the onset of major depression in adulthood.Method: Participants were 1,104 offspring of mothers enrolled during pregnancy in the Providence, R.I., site of the National Collaborative Perinatal Project. Measures of childhood family disruption and socioeconomic status were obtained before birth and at age 7. Structured diagnostic interviews were used to assess respondents' lifetime history of major depressive episode between the ages of 18 and 39. Survival analysis was used to identify childhood risks for depression onset.Results: Parental divorce in early childhood was associated with a higher lifetime risk of depression among subjects whose mothers did not remarry as well as among subjects whose mothers remarried. These effects were more pronounced when accompanied by high levels of parental conflict. independent of the respondents' adult socioeconomic status, low socioeconomic status in childhood predicted an elevated risk of depression.Conclusions: Family disruption and low socioeconomic status in early childhood increase the long-term risk for major depression. Reducing childhood disadvantages may be one avenue for prevention of depression. Identification of modifiable pathways linking aspects of the early childhood environment to adult mental health is needed to mitigate the long-term consequences of childhood disadvantage.