Spatial relational memory in 9-month-old macaque monkeys.
Spatial relational memory in 9-month-old macaque monkeys.
复制标题
9 个月大猕猴的空间关系记忆。
DOI：
10.1101/lm.97606
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发表时间：
2006
期刊：
影响因子：
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通讯作者：
Lavenex,PamelaBanta
中科院分区：
文献类型：
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作者：
Lavenex,Pierre;Lavenex,PamelaBanta
本实验评估了自由活动的9月龄和成年（11-13岁）猕猴（Macaca mulatta）的空间和非空间关系记忆。我们测试了近端地标的使用，两个不同的物体放置在一个开放的领域竞技场的中心，作为条件线索，允许猴子预测隐藏在两组三个不同的位置之一的食物奖励的位置。猴子在两种不同的条件下进行了测试：（1）当局部视觉线索标记了两组潜在的诱饵位置时，猴子可以使用局部和空间信息来区分这些位置和从未诱饵的位置;以及（2）当没有局部视觉线索标记两组潜在诱饵位置时，所以猴子必须依靠环境的空间关系表征来区分这些位置。没有9月龄或成年猴将竞技场中心的近端标志的存在与三个不同位置中的食物的存在相关联。然而，所有的猴子，歧视潜在的诱饵的位置在当地的视觉线索的存在下，从而提供了视觉辨别学习的证据。更重要的是，所有9个月大的猴子测试歧视潜在的诱饵的位置，在当地的视觉线索的情况下，从而表现出空间关系学习的证据。这些研究结果表明，空间记忆过程的特点是环境的关系表示存在早在9个月的年龄在猕猴。
This experiment assesses spatial and nonspatial relational memory in freely moving 9-mo-old and adult (11-13-yr-old) macaque monkeys (Macaca mulatta). We tested the use of proximal landmarks, two different objects placed at the center of an open-field arena, as conditional cues allowing monkeys to predict the location of food rewards hidden in one of two sets of three distinct locations. Monkeys were tested in two different conditions: (1) when local visual cues marked the two sets of potentially baited locations, so that monkeys could use both local and spatial information to discriminate these locations from never-baited locations; and (2) when no local visual cues marked the two sets of potentially baited locations, so that monkeys had to rely on a spatial relational representation of the environment to discriminate these locations. No 9-mo-old or adult monkey associated the presence of the proximal landmarks, at the center of the arena, with the presence of food in one set of three distinct locations. All monkeys, however, discriminated the potentially baited locations in the presence of local visual cues, thus providing evidence of visual discrimination learning. More importantly, all 9-mo-old monkeys tested discriminated the potentially baited locations in absence of the local visual cues, thus exhibiting evidence of spatial relational learning. These findings indicate that spatial memory processes characterized by a relational representation of the environment are present as early as 9 mo of age in macaque monkeys.