A brief motivational intervention for substance misuse in recent-onset psychosis
A brief motivational intervention for substance misuse in recent-onset psychosis
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DOI：
10.1080/09595230410001704127
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发表时间：
2004-06-01
影响因子：
3.8
通讯作者：
Clair, A
中科院分区：
文献类型：
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作者：
Kavanagh, DJ;Young, R;Clair, A
药物滥用在早期精神病中很常见，并对结果产生负面影响。对这一人群的有效干预措施所知甚少。我们报告了一项针对早期精神病药物滥用的简短干预（重新开始和生存：SOS）的试点研究，并将其与标准护理（SC）进行比较。25名年龄在18 - 35岁的早期精神病和目前滥用非阿片类药物的住院患者被随机分配到不同的条件下。在基线、6周、3、6和12个月时评估药物使用和相关问题。最后的评估不考虑条件。所有13名进行动机性访谈的SOS参与者在6个月时都报告了较少的物质使用，而SC单独为58%（7/12）。效果维持至12个月。然而，更多的SOS参与者与亲戚或伴侣住在一起，这也与更好的结果有关。参与仍然具有挑战性：39%（16/41）的人拒绝参与，38%（5/13）的SOS只建立了融洽的关系。进一步的研究将增加样本量，并解决用户粘性和潜在的混淆问题。
Substance misuse is common in early psychosis, and impacts negatively on outcomes. Little is known about effective interventions for this population. We report a pilot study of brief intervention for substance misuse in early psychosis ( Start Over and Survive: SOS), comparing it with Standard Care(SC). Twenty-five in-patients aged 18 - 35 years with early psychosis and current misuse of non-opioid drugs were allocated randomly to conditions. Substance use and related problems were assessed at baseline, 6 weeks and 3, 6 and 12 months. Final assessments were blind to condition. All 13 SOS participants who proceeded to motivational interviewing reported less substance use at 6 months, compared with 58% (7/12) in SC alone. Effects were well maintained to 12 months. However, more SOS participants lived with a relative or partner, and this also was associated with better outcomes. Engagement remained challenging: 39% (16/41) declined participation and 38% (5/13) in SOS only received rapport building. Further research will increase sample size, and address both engagement and potential confounds.