Genome-Wide SNP Analysis Reveals the Population Structure and the Conservation Status of 23 Italian Chicken Breeds
Genome-Wide SNP Analysis Reveals the Population Structure and the Conservation Status of 23 Italian Chicken Breeds
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DOI：
10.3390/ani10081441
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发表时间：
2020-08-01
期刊：
影响因子：
3
通讯作者：
Cassandro, Martino
中科院分区：
文献类型：
--
作者：
Cendron, Filippo;Perini, Francesco;Cassandro, Martino
简单总结 为了评估意大利鸡品种的保护状况和基因组变异性，我们使用单核苷酸多态性 (SNP) 分子标记进行了全基因组分析。这些结果增加了知识，并有助于制定意大利当地鸡品种的保护计划，以保护其遗传变异性。使用单核苷酸多态性 (SNP) 对意大利当地鸡品种的基因组变异进行了研究，以了解其遗传多样性和种群结构，并根据保护计划对其进行监测。使用 Affymetrix 600 K Chicken SNP Array 对来自 23 个当地品种和 4 个商业品种的总共 582 个样本进行了基因分型。一般来说，通过不同方法调查发现，与商业鸡群相比，当地鸡品种的遗传多样性水平最低。基于纯合性 (F-ROH) 的基因组近交水平在各个品种之间存在显着差异，范围从 0.121（瓦尔达内塞）到 0.607（西西里岛）。在所有品种中，纯合性短期运行（ROH）（
Simple Summary To assess the conservation status and the genomic variability of Italian chicken breeds, we carried out genome-wide analyses using single nucleotide polymorphism (SNP) molecular markers. These results increase knowledge and can aid with the development of conservation plans for local Italian chicken breeds to safeguard their genetic variability. The genomic variability of local Italian chicken breeds, which were monitored under a conservation plan, was studied using single nucleotide polymorphisms (SNPs) to understand their genetic diversity and population structure. A total of 582 samples from 23 local breeds and four commercial stocks were genotyped using the Affymetrix 600 K Chicken SNP Array. In general, the levels of genetic diversity, investigated through different approaches, were lowest in the local chicken breeds compared to those in the commercial stocks. The level of genomic inbreeding, based on runs of homozygosity (F-ROH), was markedly different among the breeds and ranged from 0.121 (Valdarnese) to 0.607 (Siciliana). In all breeds, short runs of homozygosity (ROH) (