Oral carcinoma cuniculatum presenting with moth-eaten destruction of the mandible
Oral carcinoma cuniculatum presenting with moth-eaten destruction of the mandible
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DOI：
10.1016/j.oooo.2018.01.008
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发表时间：
2018-04-01
影响因子：
2.9
通讯作者：
Li, Jiang
中科院分区：
文献类型：
--
作者：
Zhang, Chunye;Hu, Yuhua;Li, Jiang
客观的。爪形癌 (CC) 是鳞状细胞癌的一种罕见变体。我们描述了一个新病例的临床病理学结果。研究设计。这是对CC案例的文献回顾和回顾性研究。结果。 CC 的临床和影像学表现多种多样；有些病例可能难以通过活检进行准确诊断。本文报告一例发生在磨牙后区域并累及下颌骨的 CC 病例。患者是一名39岁的男性。临床上，病变表现为下颌磨牙区的溃疡性肿块。影像学结果显示，颌骨病变呈虫蚀性破坏，颌骨未见明显扩张。术后病理检查符合CC；此外，1 个 II 级淋巴结和 1 个颌下淋巴结存在转移。术后10个月和27个月分别检测到左侧软组织转移和右侧颈淋巴结转移。结论。 CC是一种罕见的上皮性恶性肿瘤，临床表现多样。 CC的诊断主要取决于病理特征。大多数CC患者预后良好；只有一小部分患者可能会出现淋巴结转移。
Objective. Carcinoma cuniculatum (CC) is a rare variant of squamous cell carcinoma. We describe the clinicopathologic findings in a new case.Study Design. This is a literature review and retrospective study of a case with CC.Results. The clinical and imaging findings of CC are diverse; some cases might be challenging to diagnose accurately by biopsy. This article reports a case of CC that occurred in the retromolar region with involvement of the mandible. The patient was a 39-year-old man. Clinically, the lesion manifested as an ulcerative mass in the mandibular molar region. Imaging results showed that the lesion in the jaw exhibited moth-eaten destruction without obvious expansion of the jaw bone. The postoperative pathologic examinations were consistent with CC; additionally, metastases were present in 1 level II lymph node and 1 submandibular lymph node. Left soft tissue metastasis and right cervical lymph node metastases were detected 10 and 27 months after surgery, respectively.Conclusions. CC is a rare epithelial malignant tumor and has variable clinical manifestations. The diagnosis of CC mainly depends on pathologic features. Most patients with CC have a good prognosis; only a small percentage of patients might experience lymph node metastasis.