Comparison of lateral-flow immunoassay and enzyme immunoassay with viral culture for rapid detection of influenza virus in nasal wash specimens from children

Comparison of lateral-flow immunoassay and enzyme immunoassay with viral culture for rapid detection of influenza virus in nasal wash specimens from children
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DOI:
10.1128/jcm.41.5.2132-2134.2003
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发表时间:
2003-05-01
影响因子:
9.4
通讯作者:
Demmler, GJ
Demmler, GJ
中科院分区:
医学2区
文献类型:
--
作者:
Cazacu, AC;Greer, J;Demmler, GJ

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通过使用2001至2002年流感季节收集的356份鼻洗标本,对两种市售流感病毒快速检测试剂盒的性能与咸水培养的性能进行了比较。总体而言,两种快速检测方法易于操作,灵敏度(70.4和72.2%)和特异性(97.7和98.3%)相当;对于这两组检测试剂盒,大多数产生假阴性结果的标本被发现正在生长乙型流感病毒。
The performance of two commercially available rapid test kits for influenza virus detection was compared to that of Aral culture by using 356 nasal wash specimens collected during the 2001 to 2002 influenza season. Overall, the two rapid tests were easy to perform and showed comparable sensitivities (70.4 and 72.2%) and specificities (97.7 and 98.3%); for both test kit groups, most of the specimens that yielded false-negative results were found to be growing influenza B virus.