Ultrasonography-guided radiofrequency ablation for the treatment of T2N0M0 papillary thyroid carcinoma: a preliminary study
Ultrasonography-guided radiofrequency ablation for the treatment of T2N0M0 papillary thyroid carcinoma: a preliminary study
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超声引导射频消融治疗T2N0M0甲状腺乳头状癌的初步研究
DOI：
10.1080/02656736.2021.1895332
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发表时间：
2021-01
影响因子：
3.1
通讯作者：
Tang Jie
中科院分区：
文献类型：
--
作者：
Xiao Jing;Zhang Yan;Zhang Mingbo;Xie Fang;Yan Lin;Luo Yukun;Tang Jie
摘要目的评价超声引导下射频消融治疗T2 N 0 M0甲状腺乳头状癌的疗效和安全性。方法本回顾性研究经中国人民解放军总医院伦理委员会批准（S2019-211-01）。我们的研究纳入了12例T2 N 0 M0 PTC患者（5例男性和7例女性，平均年龄41.0 ± 9.2岁（范围21-61岁）），这些患者不符合手术条件或拒绝手术。RFA采用移动发射技术，消融区域超出肿瘤边缘至少3 mm。超声检查在RFA前、RFA后即刻、1、3、6和12个月进行，此后每6-12个月进行一次。结果所有肿瘤均按计划切除。平均随访时间为24.1 ± 6.9个月（范围：13-33个月）。肿瘤体积由4.4 ± 2.8 ml缩小至0.3 ± 0.5 ml，体积缩小率（VRR）为（93.7 ± 7.6）%，其中2例（16.7%）肿瘤消失。随访期间未发现新发或复发肿瘤，未发现局部或远处转移。未观察到危及生命或迟发性并发症。结论RFA可能是治疗T2 N 0 M0 PTC的一种潜在替代手术方法，特别是对于那些不适合手术的患者。
Abstract Purpose To evaluate the efficacy and safety of ultrasonography (US)-guided radiofrequency ablation (RFA) for treating T2N0M0 papillary thyroid cancer (PTC). Methods This retrospective study was approved by the ethics committee of Chinese PLA General Hospital (S2019-211-01). Twelve patients with T2N0M0 PTC (five men and seven women with a mean age of 41.0 ± 9.2 years (range, 21–61 years)), who were not eligible for or refused surgery, were included in our study. RFA was performed with the moving-shot technique, and the ablation area exceeded the tumor edge by at least 3 mm. US was performed before RFA, immediately, 1, 3 , 6 and 12 months after RFA, and every 6–12 months thereafter. Results All tumors were ablated as planned. The mean follow-up duration was 24.1 ± 6.9 months (range, 13–33 months). The tumor volume decreased significantly from 4.4 ± 2.8 ml to 0.3 ± 0.5 ml, and the volume reduction rate (VRR) was (93.7 ± 7.6)% at the final follow-up with two tumors (16.7%) disappearing. New or recurrent tumors were not found, and no local or distant metastasis were detected during follow-up. No life-threatening or delayed complications were observed. Conclusion RFA may be a potential alternative to surgery for the management of T2N0M0 PTC in select patients, especially for those who are ineligible for surgery.
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DOI：
--
发表时间：
2017
期刊：
--
影响因子：
--
作者：
Kaliszewski;Diakowska;Strutyńska-Karpińska;Wojtczak;Domosławski;Balcerzak
通讯作者：
Kaliszewski;Diakowska;Strutyńska-Karpińska;Wojtczak;Domosławski;Balcerzak
影响因子：
3.8
作者：
Linos, Dimitrios;Economopoulos, Konstantinos P.;Petralias, Athanassios
通讯作者：
Petralias, Athanassios
影响因子：
6.6
作者：
Sakai, Toshihiko;Sugitani, Iwao;Yamada, Keiko
通讯作者：
Yamada, Keiko
超声引导下射频消融与手术治疗孤立性 T1bN0M0 甲状腺乳头状癌的比较研究
影响因子：
3.2
作者：
Xiao, Jing;Zhang, Yan;Tang, Jie
通讯作者：
Tang, Jie
影响因子：
4.2
作者：
Gharib, Hossein;Papini, Enrico;Vitti, Paolo
通讯作者：
Vitti, Paolo