Effect of hyperthermia on vascular functions of normal tissues and experimental tumors; brief communication.

Effect of hyperthermia on vascular functions of normal tissues and experimental tumors; brief communication.
复制标题

热疗对正常组织和实验肿瘤血管功能的影响;

DOI:
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发表时间:
1978
期刊:
Journal of the National Cancer Institute
影响因子:
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通讯作者:
C. Song
C. Song
中科院分区:
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文献类型:
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作者:
C. Song

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研究了热疗对近交系SD雄性大鼠Walker癌256、皮肤和肌肉血管体积和通透性的影响。虽然在43℃下加热1小时可以显著增加皮肤和肌肉的血管容量和血管通透性,但并没有改变肿瘤中的血管功能。正常组织中血管体积的增加表明循环的增加,这可能会增强热量的消散,从而导致热疗对正常组织和肿瘤的不同影响。
The effect of hyperthermia on vascular volume and vascular permeability of the Walker carcinoma 256, skin, and muscle of inbred SD male rats was investigated. Whereas heating at 43 degrees C for 1 hour induced a significant increase in the functional vascular volume and vascular permeability in the skin and muscle, it did not change these vascular functions in the tumors. The increased vascular volume in the normal tissues suggested an increased circulation, which may enhance the dissipation of heat and result in a differential effect of hyperthermia on normal tissues and tumors.