Isolation and structure of ciguatoxin-4A, a new ciguatoxin precursor, from cultures of dinoflagellate Gambierdiscus toxicus and parrotfish Scarus gibbus

Isolation and structure of ciguatoxin-4A, a new ciguatoxin precursor, from cultures of dinoflagellate Gambierdiscus toxicus and parrotfish Scarus gibbus
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DOI:
10.1271/bbb.60.2103
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发表时间:
1996-12-01
影响因子:
1.6
通讯作者:
Yasumoto, T
Yasumoto, T
中科院分区:
工程技术4区
文献类型:
--
作者:
Satake, M;Ishibashi, Y;Yasumoto, T

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从海洋甲藻Gambierdiscus toxicus的培养物中分离到一种新的雪卡毒素同系物--雪卡毒素-4A(ciguatoxin-4A,CTX-4A),根据光谱数据确定其结构为52-epiciguatoxin-4 B。色谱和光谱比较表明,CTX 4A与一种结构不明的同系物Scaritoxin或SG 1相同。
A new ciguatoxin congener, ciguatoxin-4A (CTX4A), was isolated from cultures of marine dinoflagellate Gambierdiscus toxicus, and its structure was elucidated to be 52-epiciguatoxin-4B on the basis of spectroscopic data. Chromatographic and spectral comparisons indicated that CTX4A was identical with a structurally unelucidated congener known as scaritoxin or SG1.