Orientation Tuning Depends on Spatial Frequency in Mouse Visual Cortex.
Orientation Tuning Depends on Spatial Frequency in Mouse Visual Cortex.
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DOI：
10.1523/eneuro.0217-16.2016
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发表时间：
2016-09
期刊：
影响因子：
3.4
通讯作者：
Yuste R
中科院分区：
文献类型：
--
作者：
Ayzenshtat I;Jackson J;Yuste R
神经元对感觉刺激的反应特性已被用于识别它们的感受野和功能映射感觉系统。在初级视皮层中，大多数神经元对视觉刺激的特定方向和空间频率具有选择性。使用双光子钙成像的神经元群体从小鼠的初级视觉皮层，我们的特点是神经元的响应特性，以各种方向和空间频率。令人惊讶的是，我们发现神经元的方向选择性实际上取决于刺激的空间频率。这种依赖性可以很容易地解释，如果一个假设空间不对称的Gabor型感受野。我们认为，在视觉皮层的第2/3层的神经元的感受野确实是空间不对称的，这种不对称性可以有效地利用视觉系统编码的自然场景。
The response properties of neurons to sensory stimuli have been used to identify their receptive fields and to functionally map sensory systems. In primary visual cortex, most neurons are selective to a particular orientation and spatial frequency of the visual stimulus. Using two-photon calcium imaging of neuronal populations from the primary visual cortex of mice, we have characterized the response properties of neurons to various orientations and spatial frequencies. Surprisingly, we found that the orientation selectivity of neurons actually depends on the spatial frequency of the stimulus. This dependence can be easily explained if one assumed spatially asymmetric Gabor-type receptive fields. We propose that receptive fields of neurons in layer 2/3 of visual cortex are indeed spatially asymmetric, and that this asymmetry could be used effectively by the visual system to encode natural scenes.