The mouse lysyl oxidase gene (Lox) resides on chromosome 18.
The mouse lysyl oxidase gene (Lox) resides on chromosome 18.
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DOI:
10.1159/000133500
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发表时间:
1993
期刊:
影响因子:
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通讯作者:
Y. S. Chang;D. Svinarich;T. Yang;S. Krawetz
中科院分区:
文献类型:
--
作者:
Y. S. Chang;D. Svinarich;T. Yang;S. Krawetz
Lysyl oxidase initiates crosslink formation of the connective tissue matrix. This enzyme can also revert the ras phenotype in mouse NIH 3T3-transformed cells. Even though lysyl oxidase may participate in many different biological processes, its chromosomal assignment in the mouse genome remains to be addressed. Southern analysis of a panel of Chinese hamster x mouse somatic cell hybrids was utilized to assign the lysyl oxidase gene (Lox) to mouse Chromosome 18.