Age‐Associated Differences in Cognitive Abilities in Adults with Down Syndrome

Age‐Associated Differences in Cognitive Abilities in Adults with Down Syndrome
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唐氏综合症成人认知能力的年龄相关差异

DOI:
10.1097/00013614-199803000-00008
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发表时间:
1998
影响因子:
0.5
通讯作者:
S. Krinsky
S. Krinsky
中科院分区:
医学4区
文献类型:
--
作者:
D. Devenny;S. Krinsky

文献摘要

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将患有唐氏综合征(DS)的轻度/中度精神发育迟滞(MR)的健康成人与其他原因导致的MR成人在WISC-R上进行比较。DS <45岁的成年人在操作子测试中的表现优于言语子测试。在DS的参与者中,观察到经典的老化模式,其中45岁的成年人与DS的年轻参与者相比,在性能子测试上有选择性下降,而言语子测试分数保持不变。其他原因导致MR的成年人在同一年龄范围内并未表现出相同的年龄相关差异。看来,患有DS的成年人在其相对认知能力领域(即非语言能力)表现出衰老的影响。对于这个群体来说,正常衰老的影响不仅可能发生得更早,而且可能对他们的整体功能产生比同龄人更大的影响。
Healthy adults with Down syndrome (DS) with mild/moderate mental retardation (MR) were compared to adults with MR from other causes on the WISC-R. Adults with DS <45 years of age did better on the performance subtests than on the verbal subtests. Among the participants with DS the classic aging pattern was observed in which adults 45 years of age had a selective decline on the performance subtests compared to younger participants with DS, while verbal subtest scores remained unchanged. Adults with MR from other causes did not show the same age-associated differences within the same age range. It appears that adults with DS show the effects of aging within their area of relative cognitive strength, that is, in nonverbal abilities. For this group, the effects of normal aging may not only occur earlier, but may also have a greater impact on their overall functioning than for their peers.